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Colorectal cancer – Red and Processed meat – Heme iron – Apparent Total N-nitroso Compounds – Lipid peroxidation

Heme-Induced Biomarkers Associated with Red Meat
Promotion of colon Cancer Are Not Modulated by the
Intake of Nitrite

Heme-Induced Biomarkers Associated with Red Meat Promotion of colon Cancer Are Not Modulated by the Intake of Nitrite

... Red and processed meat consumption is associated with the risk of colorectal ...via heme/alcenal, heterocyclic amines or N-nitroso ...predict nitroso- and ...

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Targeting colon luminal lipid peroxidation limits colon carcinogenesis associated with red meat consumption

Targeting colon luminal lipid peroxidation limits colon carcinogenesis associated with red meat consumption

... between red meat intake and colorectal cancer, including heterocyclic amine formation during high- temperature cooking (13), N-nitroso compound forma- tion by endogenous ...

13

Red meat and colorectal cancer : lipid peroxidation-derived products induce different apoptosis, autophagy and Nrf2-related responses in normal and preneoplastic colon cells

Red meat and colorectal cancer : lipid peroxidation-derived products induce different apoptosis, autophagy and Nrf2-related responses in normal and preneoplastic colon cells

... ABSTRACT Red meat is a factor risk for colorectal cancer, considered as probably carcinogenic to ...humans. Red meat is associated to colorectal cancer through the ...

202

The role of red and processed meat in colorectal cancer development: a perspective

The role of red and processed meat in colorectal cancer development: a perspective

... 4.2. Heme iron and reactive oxygen species Heme iron has been implicated in intestinal cancer risk, either in combination with nitrite or alone ( Joosen et ...). Red ...

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Processed Meat and Colorectal Cancer: A Review of Epidemiologic and Experimental Evidence

Processed Meat and Colorectal Cancer: A Review of Epidemiologic and Experimental Evidence

... World Cancer Research Fund authoritative expert report states: “evidence shows that red meat probably increases risk and processed meat possibly increases risk of CRC” ...that ...

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Heme-Induced Biomarkers Associated with Red Meat Promotion of colon Cancer Are Not Modulated by the Intake of Nitrite.

Heme-Induced Biomarkers Associated with Red Meat Promotion of colon Cancer Are Not Modulated by the Intake of Nitrite.

... Red and processed meat consumption is associated with the risk of colorectal ...via heme/alcenal, heterocyclic amines or N-nitroso ...predict nitroso- and ...

13

Red and processed meat intake and cancer risk: Results from the prospective NutriNet-Santé cohort study

Red and processed meat intake and cancer risk: Results from the prospective NutriNet-Santé cohort study

... on Cancer (WHO-IARC) recently classified consumption of processed meat as “carcinogenic to humans” and consumption of red meat as “probably carcinogenic to humans”(1) The World ...

22

Cancer colorectal mtastatique

Cancer colorectal mtastatique

... altération de l’état général avec asthénie, amaigrissement, fièvre, anémie témoignant d’un cancer déjà évolué. 2. Métastases hépatiques : Les métastases hépatiques des CCR sont habituellement infra-cliniques ...

245

Le depistage du cancer colorectal

Le depistage du cancer colorectal

... La colographie virtuelle pourrait voir sa sen- sibilité améliorée dans les mois à venir pour le dépistage des sujets asymptomatiques à risque moyen de cancer colorectal. Les études sont nombreuses. Le ...

6

Probiotiques et cancer : exemple du cancer colorectal

Probiotiques et cancer : exemple du cancer colorectal

... au cancer colorectal restent, pour l’instant, ...le cancer colorectal, confirment le niveau de preuve « convaincant », sachant que seuls les niveaux de preuve convaincants ou probables ...

76

Meat processing and colon carcinogenesis: Cooked, nitrite-treated and oxidized high-heme cured meat promotes mucin depleted foci in rats

Meat processing and colon carcinogenesis: Cooked, nitrite-treated and oxidized high-heme cured meat promotes mucin depleted foci in rats

... Abbreviations of diet names: CON-10, control diet; All experimental diets contained 55% processed meat: LCNA, [light cooked meat with nitrite, anaerobic]; DCNA, [dark cooked meat with ni[r] ...

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Meat processing and colon carcinogenesis: cooked, nitrite-treated, and oxidized high-heme cured meat promotes mucin-depleted foci in rats.

Meat processing and colon carcinogenesis: cooked, nitrite-treated, and oxidized high-heme cured meat promotes mucin-depleted foci in rats.

... a processed meat that contains heme and nitrite, and has been cooked at 70 C and exposed to air for five days at ° 4 C, can increase the number of preneoplastic lesions in rats, ...

16

Microbiota, inflammation and colorectal cancer

Microbiota, inflammation and colorectal cancer

... commensal and periodontal pathogen associated with diverse diseases [ 147 ...] and is found in higher proportion in CRC tumors compared to adjacent normal tissues [ 148 , 149 ...size and number, ...

28

Le cancer colorectal

Le cancer colorectal

... Ce panorama montre l’étendue du domaine des recherches soutenues par l’INCa et les Ministères de tutelles depuis 2005 et l’importance de l’effort finan- cier ; les projets listés précédemment totalisent près de 12 ...

1

Stearoyl-CoA Desaturase-1 drives cancer malignancy via lipid desaturation and peroxidation after anti-angiogenic treatment withdrawal

Stearoyl-CoA Desaturase-1 drives cancer malignancy via lipid desaturation and peroxidation after anti-angiogenic treatment withdrawal

... in cancer is actually the most contemporary topic of drug ...of cancer cells to sustain proliferation and survival pave the way for innovative therapeutic ...of cancer adaptation and ...

1

Potential carcinogenic mechanisms by red and cured meat

Potential carcinogenic mechanisms by red and cured meat

... In all our previous rats studies, carcinogenesis promotion by fresh red meat or by heme was associated with fat peroxidations biomarkers: associated with fat peroxidations biomarkers: [r] ...

32

Gut microbiota imbalance and colorectal cancer

Gut microbiota imbalance and colorectal cancer

... mutations and protein-DNA crosslinking, all contributing to genomic instability in CRC [185-187] ...cells, and the use of inhibitors of ROS and NOS can prevent this effect, supporting the role of ...

19

Red wine extract disrupts Th17 lymphocyte differentiation in a colorectal cancer context

Red wine extract disrupts Th17 lymphocyte differentiation in a colorectal cancer context

... qualitative and quantitative analysis by HPLC of ...(catechin and procyanidin dimers), stilbenes (resveratrol and its glycosylated form piceid) and flavonols ...qualitative and ...

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Evaluation of the effect of spinosad on lipid peroxidation and antioxidant markers in female mice

Evaluation of the effect of spinosad on lipid peroxidation and antioxidant markers in female mice

... Jagota and Dani using the Folin reagent and a standard range of ascorbic acid ...acid and centrifugation, the supernatant is mixed with distilled water and Folin's ...sample and the ...

7

Meat and cancer: haemoglobin and haemin in a low calcium diet  promote colorectal carcinogenesis at the aberrant crypt stage in rats

Meat and cancer: haemoglobin and haemin in a low calcium diet promote colorectal carcinogenesis at the aberrant crypt stage in rats

... water, and forms insoluble polymers at low pH in the stomach ...absorption and reaches the colon. In the colon, haemin induces lipid peroxidation and yields the cytotoxic compound ...

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