Clinical-grade
Clinical-grade mesenchymal stromal cells produced under various good manufacturing practice processes differ in their immunomodulatory properties: standardization of immune quality controls.
... validate clinical-grade ...of clinical-grade MSC, IDO activity should [ ] thus also be finely evaluated in vivo as a biomarker for the immunosuppressive activity of MSC in forthcoming ...
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Human serum and platelet lysate are appropriate xeno-free alternatives for clinical-grade production of human MuStem cell batches
... in clinical trials [ 74 ]. Clinical-grade production of purified fractionated heparin, an animal-derived bio- logical product, is highly regulated (monographs in the European Pharmacopeia and good ...
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Immunoregulatory properties of clinical grade mesenchymal stromal cells: evidence, uncertainties, and clinical application.
... produce clinical grade MSCs but, so far, it is not known if one given MSC is more efficient than ...to clinical efficacy and clinically relevant immunomonitoring approaches for MSC-treated patients ...
8
Proteasomal Indoleamine 2,3-Dioxygenase Degradation Reduces the Immunosuppressive Potential of Clinical Grade-Mesenchymal Stromal Cells Undergoing Replicative Senescence
... of clinical-grade MSCs from bone marrow (BM-MSCs) or adipose tissue (ASCs) has paved the way for their therapeutic ...500 clinical trials evaluating MSC therapy in multiple clinical settings ...
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Clinical-grade production and safe delivery of human ESC derived RPE sheets in primates and rodents
... 12 Different strategies were proposed to generate RPE sheets including the use or not of scaffolds to reconstruct the RPE epithelium in vitro (19, 38, 39). The group of M. Takahashi developed a RPE sheet without ...
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Predictors of good outcome in good grade subarachnoid hemorrhage
... WFNS grade, greater SAH clot thickness on admission CT scan, posterior circulation and larger aneurysm, intraventricular hemorrhage, intracerebral hemorrhage, admission systolic hypertension, history of ...
42
Requirements for cfd-grade experiments for nuclear reactor thermalhydraulics
... Therefore, an experiment which minimizes both 𝜹 𝒊𝒏𝒑𝒖𝒕 and 𝜹 𝑫 also minimizes 𝒖 𝒗𝒂𝒍 and provides more information on the accuracy of the model. One can consider that: A CFD-grade experiment should provide the ...
21
Modelling of necking during creep of grade 91 steel
... The fracture criterion is usually defined as the ratio of the final necking section to the initial cross section (r c = snecking / S initial ). For creep tests at temperatures between 500 and 600°C on Grade 91, r ...
9
Anodic oxidation of p-phenylenediamines in battery grade electrolytes
... solid state with an overall reversible two-electron reaction making them interesting for positive electrode applications [12-14]. In light of the opportunity offer by this new family of insertion compounds and to go ...
21
Caractérisation morphologique et immunohistochimique des tumeurs neuroendocrines pulmonaires de haut grade opérées
... Une réflexion sur l’uniformisation de la classification des néoplasies neuroendocrines entre les différents organes est en cours de réflexion, notamment par le Centre International de Recherche sur le Cancer (CIRC) et ...
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Méthodologie des essais cliniques randomisés évaluant les traitements des gliomes de haut-grade
... Notre recherche Pubmed a permis d’identifier 310 articles (Figure 4). Après la lecture des résumés, 183 études se sont avérées non éligibles parce qu’elles ne répondaient pas à l’ensemble des critères d’inclusion. La ...
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FLUIDES DE SECOND ET TROISIEME GRADE EN DIMENSION TROIS : SOLUTION GLOBALE ET REGULARITE
... de grade 2 avec α 1 + α 2 6= 0, nous n’avons pas, dans le cas du grade 3, de d´ ecroissance exponentielle en fonction du temps de la norme H 1 de la vitesse pour toute donn´ ...
221
New basement wall designs for below-grade living space
... This technique could well have wide applica- tion in Canada, both in connection with house basements and with other subgrade structures where significant economies may result from th[r] ...
46
Urine in clinical proteomics.
... Monitoring) to validate potential biomarkers previously identified by nanoLC-MS/MS in the discovery phase on a reduced number of patients. MRM based approaches allow to quantify with high sensitivity and selectivity ...
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Prise en charge neurochirurgicale des gliomes de bas grade de la fosse crbrale postrieure de l'enfant
... 2.... Récidive Récidive Récidive Récidive :::: L’apparition des récidives est fonction du type histologique, de l’âge du patient et de la nature de l’exérèse tumorale. La date d’apparition des récidives pour ...
163
Measures of comprehension for Czech first-to fourth-grade pupils
... Validity All new comprehension tasks show positive statistically significant correlation to standardized rea- ding comprehension measure RCT (Caravolas & Volín, 2005) even after controlling for grade status. ...
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Industrial grade model checking: use Cases, constraints, tools and applications
... To cite this version : Clabaut, Mathieu and Ge, Ning and Breton, Nicolas and Jenn, Eric and Delmas, Rémi and Fonteneau, Yoann Industrial grade model checking: use Cases, constraints, [r] ...
9
Diagnostic de boiterie de faible grade à l’aide de capteurs inertiels de locomotion chez le cheval
... du grade de boiterie attribué par le vétérinaire, les échantillons étaient de très petites tailles et les conclusions tirées à partir de ces données sont difficilement significatives et doivent être interprétées ...
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Evolution des techniques chirurgicales dans la prise en charge des gliomes de bas grade sustentoriels de ladullte
... bas grade sus tentoriels symptomatiques de l’adulte est encore très controversée ...bas grade associée à une diminution des risques dus aux traitements, a transformé l’attitude abstentionniste classique en ...
148
Clinical Pharmacokinetics of Daptomycin
... daily daptomycin in critically ill patients undergoing continuous renal replacement therapy. Vilay AM, Grio M, Depestel DD, Sowinski KM, Gao L, Heung M, et al[r] ...
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