class II
Melanosomal targeting sequences from gp100 are essential for MHC class II-restricted endogenous epitope presentation and mobilization to endosomal compartments
... MHC class II ...MHC class II ...MHC class II–mediated ...MHC class II– mediated presentation ...MHC class II presentation whereas deletion of this ...
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Cathepsin S regulates class II MHC processing in human CD4+ HLA-DR+ T cells
... Pulse-chase and immunoprecipitation Radiolabeling experiments were conducted as previously described(21). Briefly, cells were washed and incubated in methionine-free medium (Gibco) for 1 hour at 37°C. During the last 10 ...
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Absence of MHC class II on cDC1 dendritic cells triggers fatal autoimmunity to a cross-presented self-antigen
... Sandrine Henri 1 * † , Bernard Malissen 1,2 * † Conventional dendritic cells expressing the XCR1 chemokine receptor (cDC1s) excel at cross-presentation. Here, we developed and used a mouse model in which a Cre ...
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Sub-nanosecond tryptophan radical deprotonation mediated by a protein-bound water cluster in class II DNA photolyases
... in class II DNA photolyases Pavel Müller,* ‡a Elisabeth Ignatz, ‡b Stephan Kiontke, ¶b Klaus Brettel a and Lars-Oliver Essen* b Class II DNA photolyases are flavoenzymes occurring in both ...
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A biochemical study of Class II MHC and cytochrome P-450scc proteins
... Expression of a Class II Major Histocompatibility Complex (MHC) Heterodimer in a Lipid-linked Form with Enhanced Peptide/Soluble MHC Complex Formation at Low pH. Maturatio[r] ...
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Determination of class II peptide-MHC repertoires and recognition via large yeast-displayed libraries
... of class II prediction algorithms without alteration of underlying training algorithm architectures, especially for poorly characterized ...ideal class II MHC prediction algorithm may be ...
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MELOE-1 Antigen Contains Multiple HLA Class II T Cell Epitopes Recognized by Th1 CD4+ T Cells from Melanoma Patients
... these class II epitopes could be naturally processed from MELOE-1 whole protein and identified minimal epitopes derived from each region of MELOE-1, and presented in four distinct HLA ...
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Class II histone deacetylases: versatile regulators.
... of class II HDACs have provided important insights into how chroma- tin controls transcription and have revealed unexpected biological functions for ...which class II HDACs play crucial ...
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Interaction between estrogen and interferon gamma signaling pathways in the regulation of major histocompatibility complex class ii expression in breast cancer cells
... the class II-associated Ii peptide (CLIP). Then the MHC-II+CLIP complex is joined by a chaperone protein that facilitates the replacement of CLIP for an antigenic peptide, this chaperone also ...
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T84-intestinal epithelial exosomes bear MHC class II/peptide complexes potentiating antigen presentation by dendritic cells
... GT. Intestinal epithelial cells use two distinct pathways for HLA class II antigen processing. J Clin Invest 1997;100:204-215. 14. Welt S, Divgi CR, Real FX, Yeh SD, Garin-Chesa P, Finstad CL, Sakamoto J, ...
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The complex pattern of genetic associations of leprosy with HLA class I and class II alleles can be reduced to four amino acid positions
... HLA class I/II-leprosy risk factor(s) has been a matter of longstanding scientific ...HLA class I and class II genes, we are able to provide a unifying view of the complex relationship ...
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Susceptibility to hantavirus infection and MHC class II gene diversity in rodents
... MHC, Class II genes are known for their role in Puumala Hantavirus infections severity in ...two class II MHC genes (DQA and DRB) at different evolutionary scales in rodents in relation with ...
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Antiviral CD8⁺ T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion
... HLA class I molecules. Yet, whether CD8 + T cells restricted by HLA class II exist in natural human viral infections and exert antiviral functions is ...the class II-restricted CD8 + T ...
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MHC Class II tetramers and the pursuit of antigen-specific T cells: define, deviate, delete.: MHC Class II tetramers
... 5. Kotzin, B.L., Falta, M.T., Crawford, F., Rosloniec, E.F., Bill, J., Marrack, P., and Kappler, J., Use of soluble peptide-DR4 tetramers to detect synovial T cells specific for cartilage antigens in patients with ...
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Negative relationships between cellular immune response, Mhc class II heterozygosity and secondary sexual trait in the montane water vole
... We used the Mhc genotypes characterized at two class II genes (Dqa and Drb) and published in Tollenaere et al. (2008). We estimated immune responsiveness as the mag- nitude of cell-mediated immune response ...
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Class II MHC Self-Antigen Presentation in Human B and T Lymphocytes
... via class II ...constitutive class II MHC expression and defined lysosomal protease expression and activity ...surface class II MHC expression and, like EBV- transformed B cells, ...
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Class II histone deacetylases are directly recruited by BCL6 transcriptional repressor.
... with class II HDACs in vivo ( 22 ...with class II HDACs both directly through its C- terminal ZF region (and to a lesser extent, its BTB/POZ domain) and indirectly by recruiting several ...
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Analyse du rôle de la dégradation du facteur CIITA (class II transactivator) sur son potentiel d'activation des gènes de classe II du complexe majeur d'histocompatibilité
... Des travaux anterieurs de notre laboratoire ont indiques que 1'isoforme III de CIITA est degrade par le systeme ubiquitine-proteasome, avec une demi-vie de 30-40 minutes, et que le dom[r] ...
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EFFECTS CLASS OBESE I, II, III HOUSEWIFES ON THE SYSTEM CARDIO-RESPIRATORY CAPACITY
... obese Class I, II and III based on their BMI thing confirmed by Carolyn Coker Ross (Carolyn Coker Ross, 2009)and Liane Summerfield (Liane Summerfield, ...of class I which is insufficient adapted to ...
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EFFECTS CLASS OBESE I, II, III HOUSEWIFES ON THE SYSTEM CARDIO-RESPIRATORY CAPACITY
... obese Class I, II and III based on their BMI thing confirmed by Carolyn Coker Ross (Carolyn Coker Ross, 2009)and Liane Summerfield (Liane Summerfield, ...of class I which is insufficient adapted to ...
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