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Chronic liver disease

Pharmacokinetics in patients with chronic liver disease and hepatic safety of incretin-based therapies for the management of type 2 diabetes mellitus.

Pharmacokinetics in patients with chronic liver disease and hepatic safety of incretin-based therapies for the management of type 2 diabetes mellitus.

... 2. Literature search To identify relevant studies in this narrative review, an extensive literature search of MEDLINE (based on titles and abstracts) was performed from January 2005 to July 1st 2014, with the names of ...

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Increased brain lactate is central to the development of brain edema in rats with chronic liver disease

Increased brain lactate is central to the development of brain edema in rats with chronic liver disease

... with chronic liver ...acute liver failure, therapeutic interventions, such as mild hypothermia and albumin dialysis, have shown to reduce cerebral lactate along with brain edema and the development ...

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Brain edema in acute liver failure and chronic liver disease: Similarities and differences

Brain edema in acute liver failure and chronic liver disease: Similarities and differences

... Parkinson’s disease (Song et ...Wilson’s disease demonstrated that Alzheimer type II astrocytes originate from the fibrous type of astroglia (Bertrand et ...

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Stimulating healthy tissue regeneration by targeting the 5-HT₂B receptor in chronic liver disease.

Stimulating healthy tissue regeneration by targeting the 5-HT₂B receptor in chronic liver disease.

... whole liver up to 4 hrs post PHX in WT and KO mice (d,e). Liver TGFβ1 mRNA levels were quantified in KO and WT mice up to 72 hrs post PHX ...(f). Liver/body weight ratio was calculated in mice ...

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Pathogenic role of IL-15 in non-alcoholic fatty liver disease

Pathogenic role of IL-15 in non-alcoholic fatty liver disease

... metabolism, liver participates in amino acids degradation to supply both, carbohydrates and fatty acids (FAs) metabolic pathways, and protein ...acute liver injury. In patients with ascites and ...

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Reduced Incidence and Better Liver Disease Outcomes among Chronic HCV Infected Patients Who Consume Cannabis

Reduced Incidence and Better Liver Disease Outcomes among Chronic HCV Infected Patients Who Consume Cannabis

... on chronic liver disease (CLD) from Hepatitis C Virus (HCV) infection, the most common cause of CLD, has been ...of chronic liver diseases (alcohol, hemochromatosis, NAFLD, PBC, HBV, ...

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An Age-Calibrated Classification of Chronic Kidney Disease.

An Age-Calibrated Classification of Chronic Kidney Disease.

... Kidney Disease Epidemiology Collaboration) equations as the pre- ferred methods for estimating GFR from serum creati- nine, cystatin C, or both and recommended estimating albuminuria from albumin-to-creatinine ...

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Genetic basis of chronic mucocutaneous candidiasis disease in humans

Genetic basis of chronic mucocutaneous candidiasis disease in humans

... the disease is chronic, and characterized by relapsing and recurrent infectious manifestations at the barrier ...a disease only responsible for mucocutaneous symptoms, pyogenic infections of the ...

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Azacytidine mitigates experimental sclerodermic chronic graft-versus-host disease

Azacytidine mitigates experimental sclerodermic chronic graft-versus-host disease

... Methods: Here, we assessed the impact of azacytidine (AZA) on cGVHD in a well-established murine model of sclerodermic cGVHD (B10.D2 (H-2d) → BALB/cJ (H-2d)). Results: The administration of AZA every 48 h from day +10 to ...

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Azacytidine prevents experimental sclerodermic chronic graft-versus-host disease

Azacytidine prevents experimental sclerodermic chronic graft-versus-host disease

... sclerodermic chronic graft-versus-host disease Gilles Fransolet 1 , Grégory Ehx 1 , Joan Somja 2 , Ludovic Belle 1 , Pierre-Vincent Drion 3 , Stéphanie Humblet-Baron 4 , Yves Beguin 1, 5 , and Frédéric ...

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Chronic Kidney Disease: call for an age-adapted definition

Chronic Kidney Disease: call for an age-adapted definition

... ABSTRACT Current criteria for the diagnosis of CKD in adults include persistent signs of kidney damage, such as increased urine albumin-to-creatinine ratio or a GFR below the threshold of 60 ml/min per 1.73 m 2 . This ...

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Targeted therapy in eosinophilic chronic obstructive pulmonary disease

Targeted therapy in eosinophilic chronic obstructive pulmonary disease

... heterogeneous disease with many different clinical ...of chronic airway diseases given its relatively inaccurate diagnostic criteria ( particularly the lack of clear-cut thresholds for quantitative ...

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Chronic kidney disease.  Part I: epidemiology, pathophysiology, complications

Chronic kidney disease. Part I: epidemiology, pathophysiology, complications

... • Extrapolate current rate of decline: will pts need RRT in their life time?.. Extrapolate current rate of decline: will pt need RRT in their life time[r] ...

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Chronic pain and pain processing in Parkinson’s disease

Chronic pain and pain processing in Parkinson’s disease

... experiencing spontaneous pain or in pain-free conditions (Defazio et al., 2013 for review). Protocols have included quantitative sensory testing to measure subjective pain thresholds for different pain modalities, ...

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Roles of Ceramides in Non-Alcoholic Fatty Liver Disease

Roles of Ceramides in Non-Alcoholic Fatty Liver Disease

... (muscles, liver, pancreatic ß-cells) leads to the synthesis of specific lipids, such as sphingolipids (SL) which interfere with insulin ...the liver (adipose tissue lipolysis and hepatic lipogenesis) is an ...

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Respiratory sympathetic modulation is augmented in chronic kidney disease

Respiratory sympathetic modulation is augmented in chronic kidney disease

... While we did not see elevated baseline tSNA or perfusion pressures in the juvenile LPK at 5 weeks of age, our previous work in both young and adult LPK (7 and 14 weeks) show increased SNA, including recordings from ...

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SERPINA1 Z allele is associated with cystic fibrosis liver disease

SERPINA1 Z allele is associated with cystic fibrosis liver disease

... 17. Pan W. Extending the Iterative Convex Minorant Algorithm to the Cox Model for Interval- Censored Data. Journal of Computational & Graphical Statistics. 1999;8:109--120. 18. Torres-Duran M, Lopez-Campos JL, ...

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Nonalcoholic Fatty Liver Disease: Modulating Gut Microbiota to Improve Severity?

Nonalcoholic Fatty Liver Disease: Modulating Gut Microbiota to Improve Severity?

... NAFLD liver alterations (i.e. steatosis and ballooning), liver triglyceride and insulin- resistance 125 ...increased liver TLR4 gene expression and NLRP3 inflammasome 45 , Quercitin restored their ...

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Ketoacid Analogues Supplementation in Chronic Kidney Disease and Future Perspectives

Ketoacid Analogues Supplementation in Chronic Kidney Disease and Future Perspectives

... during chronic kidney disease ...Renal Disease study, the largest RCTs, failed to demonstrate a benefit in the primary outcome of the decline rate for the glomerular filtration ...

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Nurse-like cells impact on disease progression in chronic lymphocytic leukemia

Nurse-like cells impact on disease progression in chronic lymphocytic leukemia

... of disease re flected more faithfully than ‘crude accumulation’ of leukemic cells within tissues, and the amount of CD163 + macrophages in these patients (Supplementary Figure ...

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