Chronic hepatitis B.
Remodeling of B-Cell Subsets in Blood during Pegylated IFNα-2a Therapy in Patients with Chronic Hepatitis B Infection
... in chronic hepatitis B (CHB) infection is HBsAg ...though B cells are major mediators of a posi- tive clinical outcome, their modulation during Peg-IFN- α therapy has not yet been ...
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DNA vaccine: a promising new approach for chronic hepatitis B therapy.: DNA Vaccine for hepatitis B therapy
... influenza B, malaria, tuberculosis, SIV, HSV, HIV, HCV, ...for chronic hepatitis B for immunotherapy, since it is able to activate not only B but, importantly, also T arm of specific ...
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Impact of Highly Active Antiretroviral Therapy on Chronic Hepatitis B Serological Markers among Senegalese HIV Co-infected Children
... In Senegal, data are scarce in the pediatric HIV-HBV co-infected children. 1.2. Objectives of the Study The objective of this study was to investigate the prevalence of HBV infection in children with HIV infection, and ...
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Safety and immunogenicity of the therapeutic vaccine TG1050 in chronic hepatitis B patients: a phase 1b placebo-controlled trial
... were chronic hepatitis B (CHB) infected, male or female, ages 18–65 years receiving nucleo(s)ides treatment (ente- cavir (ETV) or tenofovir (TDF) for at least 2 years (duration of NUC ...(HIV), ...
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Mechanism of viral persistence and resistance to nucleoside and nucleotide analogs in chronic Hepatitis B virus infection
... vaccine, chronic HBV infection remains a major public health problem ...are chronic carriers of the virus, and more than one billion have been in contact with HBV (Lee, ...1997). Chronic carriers are ...
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Persistence of cccDNA during the natural history of chronic hepatitis B and decline during adefovir dipivoxil therapy.
... resolved chronic hepatitis B (HBsAg seroconverters, Figure 2A), it may not be necessary to completely eradicate cccDNA to establish long-term control of HBV ...
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Antiviral therapy of chronic hepatitis B.
... negative chronic hepatitis B (see table 2) Standard IFN administration was the only treatment available until the end of the ...of chronic hepatitis ...
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Stepwise process for the development of entecavir resistance in a chronic hepatitis B virus infected patient.: Mechanism of entecavir resistance
... of Chronic Hepatitis ...for chronic HBV infection: Lamivudine (L- deoxycitydine analog), adefovir (adenosine monophosphate analog), and entecavir (deoxyguanosine ...
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Coexistence of circulating HBsAg and anti-HBs antibodies in chronic hepatitis B carriers is not a simple analytical artifact and does not influence HBsAg quantification
... CI: -0.19; -0.14) throughout the quantification range (fig. 2B). The results provided by the Liaison-XL were constantly and significantly lower than those by the Architect assay (p=0.04). Characteristics of patients ...
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Diagnostic accuracy of ShearWave Elastography compared to Transient Elastography for the non-invasive assessment of liver fibrosis in chronic hepatitis B or C
... intercostal spaces. The SWE box was placed guided by real-time B-mode ultrasound image, at least 2 cm deeper than the Glisson’s capsule and in an area free of large vessels. Patients were asked to breath slowly ...
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New virologic tools for management of chronic hepatitis B and C.: New Virological Tools
... quantify hepatitis B surface and hepatitis C core antigens, and point-of-care tests and alternatives to biologic tests that require whole- blood samples obtained by venipuncture have been ...
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Chronic hepatitis B and HIV care: the key-role of the doctor-patient relationship
... l’hépatite B, la relation entre les patients subsahariens et leur médecin est centrale dans l’adéquation de leur prise en charge avec leurs besoins et leurs ...
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Fine characterization of intrahepatic NK cells expressing natural killer receptors in chronic hepatitis B and C.: NK cells in chronic hepatitis C and hepatitis B
... and viral load in HCV and HBV patients. To pin point this correlation, we observed that the viral load was correlated negatively with CD3 - CD56 dim NKG2A + cells subset. Taking in account that i) CD56 + NKG2A + cells ...
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CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus
... Chronic hepatitis B virus (HBV) infection is prevalent, deadly, and seldom cured due to the persistence of viral episomal DNA (cccDNA) in infected ...
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Correlation of serum hepatitis B core-related antigen with hepatitis B virus total intrahepatic DNA and covalently closed circular-DNA viral load in HIV–hepatitis B coinfection
... Testoni B, Lebossé F, Scholtes C, Berby F, Miaglia C, Subic M, et ...Serum hepatitis B core-related antigen (HBcrAg) correlates with covalently closed circular DNA transcriptional activity in ...
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Hepatitis B virus resistance to antiviral drugs: where are we going?
... of chronic hepatitis B has been made during the last decade with the development of antivirals that inhibit viral polymerase ...for chronic hepatitis ...
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Emerging drugs for hepatitis B.
... Results of Telbivudine administration The safety, antiviral activity, and pharmacokinetics of Telbivudine have been assessed in 43 adults with hepatitis B e antigen-positive chronic hepatitis ...
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Association of Hepatitis B Core-Related Antigen and Antihepatitis B Core Antibody With Liver Fibrosis Evolution in Human Immunodeficiency Virus-Hepatitis B Virus Coinfected Patients During Treatment With Tenofovir
... of hepatitis B e antigen (HBeAg) and hepatitis B surface antigen (HBsAg), are stable for many treated coinfected patients and with their varying correlation with liver fibrosis [ 14 , 15 ], ...
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New pandemics: HIV and AIDS, HCV and chronic hepatitis, Influenza virus and flu
... cation on a Δvif background [67]. Simon Wain-Hobson (Institut Pasteur, Paris, France) spoke on mechanistic par- allels between cytidine and adenosine deamination of viral nucleic acids. The APOBEC3G enzyme deaminates ...
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Treatment of HEV Infection in Patients with a Solid-Organ Transplant and Chronic Hepatitis
... No other antiviral therapy is presently known to be effective against a chronic HEV infection. Sofosbuvir was shown to have antiviral activity against HEV in vitro [ 192 ] but had limited efficacy in HEV-infected ...
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