chronic hepatitis
Plasma carnitine is associated with fatigue in chronic hepatitis C but not in irritable bowel syndrome
... of chronic liver disease (alcoholism, chronic hepatitis B, Wilson’s disease, hepatotoxic drugs, haemochromatosis, α1 antitrypsin deficiency, autoimmune chronic active ...or chronic ...
30
Persistence of cccDNA during the natural history of chronic hepatitis B and decline during adefovir dipivoxil therapy.
... resolved chronic hepatitis B (HBsAg seroconverters, Figure 2A), it may not be necessary to completely eradicate cccDNA to establish long-term control of HBV ...
25
Remodeling of B-Cell Subsets in Blood during Pegylated IFNα-2a Therapy in Patients with Chronic Hepatitis B Infection
... Interestingly, we found a sustained increase in sCD30 levels triggered by Peg-IFN- α, which correlated with the changes in B-cell subsets. The CD30/CD30L pathway plays a major role in immunological processes, especially ...
18
IFI35, mir-99a and HCV Genotype to Predict Sustained Virological Response to Pegylated-Interferon Plus Ribavirin in Chronic Hepatitis C
... compared to normal controls and patients with chronic hepatitis B [ 40 ]. This discrepancy may explain the low level of serum mir-99a detected in our cohort. Circulating mir-23a was sug- gested to be ...
20
Chronic hepatitis C virus infection, a new cardiovascular risk factor?
... A retrospective study from the Taiwan National Health Insurance Program included 3,113 subjects with a newly detected HCV infection and 12,452 age- and gender-matched subjects without HCV infection followed up to 5 years ...
20
Effectiveness and tolerability of pegylated interferon alfa2b in combination with ribavirin for treatment of chronic hepatitis C: the PegIntrust study
... Results Patient characteristics and disposition In total, 239 patients with chronic hepatitis C were screened by 64 physicians (internists and gastroenterolo- gists) at 46 centres in Belgium. Twenty ...
7
Ribavirin for Chronic Hepatitis Prevention among Patients with Hematologic Malignancies
... After SOT, chronic hepatitis develops in 60% of untreated HEV-infected patients (3). Here, we show that patients with hematologic malignancies are also at risk for chron- ic HEV infection. SOT patients ...
5
Chronic hepatitis C virus infection and pathogenesis of hepatocellular carcinoma
... induces chronic hepatitis and HCC by altering NF- κB signaling in both hepatocytes and ...virus-induced chronic hepatitis and HCC as compared to healthy liver ...
14
DNA vaccine: a promising new approach for chronic hepatitis B therapy.: DNA Vaccine for hepatitis B therapy
... for chronic hepatitis B for immunotherapy, since it is able to activate not only B but, importantly, also T arm of specific antiviral immune responses, which is crucial for resolution of HBV infection ...
8
Impact of Highly Active Antiretroviral Therapy on Chronic Hepatitis B Serological Markers among Senegalese HIV Co-infected Children
... among chronic hepatitis b co-infected children, we recommend close monitoring of children’s immuno-virological status, liver enzyme and serological hepatitis b ...
8
Safety and immunogenicity of the therapeutic vaccine TG1050 in chronic hepatitis B patients: a phase 1b placebo-controlled trial
... Treatment of chronic hepatitis B (CHB) typically requires life-long administration of drugs. Cohort and pre- clinical studies have established the link between a functional T-cell-mounted immunity and ...
14
Antiviral therapy of chronic hepatitis B.
... 10 E 4copies/mL and elevated ALT levels that may also be fluctuating over time. Treatment endpoints differ depending on the form of chronic hepatitis B. It is currently not recommended to treat patients ...
24
Comment on Nuño Solinís R, et al. “Value of Treating All Stages of Chronic Hepatitis C: A Comprehensive Review of Clinical and Economic Evidence”
... for hepatitis C virus (HCV) infection, it is well established that many other organ systems are affected, increasing the overall burden of dis- ease [ 1 – 3 ...of chronic HCV across 354 clinical studies in ...
6
Liver stiffness diminishes with antiviral response in chronic hepatitis C.: Liver Stiffness Kinetics on HCV Therapy
... Review Chronic infection with hepatitis C virus (HCV) is the leading cause of chronic liver disease in Europe and the United ...States. Chronic hepatitis C is responsible for ...
29
Stepwise process for the development of entecavir resistance in a chronic hepatitis B virus infected patient.: Mechanism of entecavir resistance
... of Chronic Hepatitis ...for chronic HBV infection: Lamivudine (L- deoxycitydine analog), adefovir (adenosine monophosphate analog), and entecavir (deoxyguanosine ...
24
Long‐term clinical benefits of Sofosbuvir‐based direct antiviral regimens for patients with chronic hepatitis C in Central and West Africa
... Figure 2: Liver disease-related deaths over lifetime with and without treatment in mono-infected patients diagnosed with chronic hepatitis C in Cameroon (Fig. 2a), Côte d’Ivoire (Fig. 2b) and Senegal (Fig. ...
25
Regulatory T Cells in Autoimmune and Viral Chronic Hepatitis
... Introduction Chronic hepatitis can result from persistent infections with hepatotropic viruses (HBV and HCV), autoimmune respons- es to the liver (autoimmune hepatitis), or drug ...drug-induced ...
10
Cost-effectiveness model for sofosbuvir in chronic hepatitis C
... for chronic hepatitis C (CHC) § Although the model allows reporting of several types of economic outcomes, results are being reported as incremental costs per quality-adjusted life years (QALYs), in line ...
1
Mechanism of viral persistence and resistance to nucleoside and nucleotide analogs in chronic Hepatitis B virus infection
... vaccine, chronic HBV infection remains a major public health problem ...are chronic carriers of the virus, and more than one billion have been in contact with HBV (Lee, ...1997). Chronic carriers are ...
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Systematic review with meta-analysis: direct comparisons of biomarkers for the diagnosis of fibrosis in chronic hepatitis C and B
... Due to these limitations, we aimed to perform an improved systematic review, focusing on direct compar- isons between the four most frequently used, discussed and recommended tests, 3, 4, 24, 25 at least for CHC since ...
15