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cell state

Control of the Embryonic Stem Cell State

Control of the Embryonic Stem Cell State

... control cell identity in other cell ...control cell state in various cell types ( Graf and Enver, 2009; Vierbuchen et ...most cell types, then identification of the master ...

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Cell-State-Specific Metabolic Dependency in Hematopoiesis and Leukemogenesis

Cell-State-Specific Metabolic Dependency in Hematopoiesis and Leukemogenesis

... Metabolic state influences cell state and metabolism must be adapted to support specific cell ...particular cell state (Cairns et ...proliferative cell populations and ...

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Targeting a cell state common to triple‐negative breast cancers

Targeting a cell state common to triple‐negative breast cancers

... transcriptional cell state might be a viable strategy to find novel therapies for this highly aggressive ...targeting cell states could be a viable strategy to discover novel treatment ...

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Cell-State Transitions Regulated by SLUG Are Critical for Tissue Regeneration and Tumor Initiation

Cell-State Transitions Regulated by SLUG Are Critical for Tissue Regeneration and Tumor Initiation

... stem cell activity and differentiation can lead to developmental defects and ...of cell-state transitions in vitro to gain insights into how SLUG/SNAI2, a key developmental transcription factor, ...

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Cell State Identication by Mass, Density, and volume

Cell State Identication by Mass, Density, and volume

... several cell generations to ultimately promote cell survival through poor conditions (the example shown in this section), and (2) A rapid size change for which nearly all cells die in response to an osmotic ...

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Comprehensive benchmarking reveals H2BK20 acetylation as a distinctive signature of cell-state-specific enhancers and promoters

Comprehensive benchmarking reveals H2BK20 acetylation as a distinctive signature of cell-state-specific enhancers and promoters

... examined cell lines and also in embryonic forebrain tis- ...highlighting cell-type-specific ...of cell-type ...with cell-state-specific expression changes than H3K27ac, with TGF-beta ...

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A driver role for GABA metabolism in controlling stem and proliferative cell state through GHB production in glioma

A driver role for GABA metabolism in controlling stem and proliferative cell state through GHB production in glioma

... stem cell · ALDH5A1 · GABA · 5-hmC · Valproate Introduction Tumor development is a complex process mixing clonal selection and dynamic changes in cell states including phe- notypic differentiation of cancer ...

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State-to-state dissociation photoionization of molecular nitrogen : the full story

State-to-state dissociation photoionization of molecular nitrogen : the full story

... direct state-of-the-art experimental measurements and high ab initio calculations to highlight the roles of the excited states of N 2 + in the predissociation phenomena of the C 2 ∑u + ...into ...

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Cell labeling with magnetic nanoparticles: Opportunity for magnetic cell imaging and cell manipulation

Cell labeling with magnetic nanoparticles: Opportunity for magnetic cell imaging and cell manipulation

... after cell internalization ...magnetized cell creates a strong localized magnetic inhomogeneity in the uniform magnetic field of the MR ...a cell (loaded with approximately 5 pg of iron) and falls to ...

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Cell fractionation

Cell fractionation

... 10. Membrane fraction resuspension can be difficult. Passing the sample through the needle of a syringe several times can optimize this step. 11. When studying a poorly characterized protein, it is important to compare ...

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The Immune Microenvironment in Clear Cell Renal Cell Carcinoma : The heterogeneous immune contextures accompanying CD8+ T cell infiltration in clear cell Renal Cell Carcinoma

The Immune Microenvironment in Clear Cell Renal Cell Carcinoma : The heterogeneous immune contextures accompanying CD8+ T cell infiltration in clear cell Renal Cell Carcinoma

... Regarding the ccRCC CD4+ TIL compartment, we found some unexpected phenotypic traits. First, we found an almost exclusive up-regulation of CD69 (early AM) and not of other AM such as CD38, CD40L and ICOS. The former ...

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Forcing alpha-cell-mediated beta-cell regeneration

Forcing alpha-cell-mediated beta-cell regeneration

... age-/sex-matched animals) were challenged with glucose. Induced animals perform better than controls with a lower peak in glycaemia and a faster return to euglycemia, suggestive of an increased β-like cell mass ...

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Cell sorting by deterministic cell rolling

Cell sorting by deterministic cell rolling

... deterministic cell rolling represents a new method of affinity cell separation, enabling effective cell capture, easy cell recovery, and highly scalable parallelization in a passive ...Many ...

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Chemomechanics at cell-cell and cell-matrix interfaces critical to angiogenesis

Chemomechanics at cell-cell and cell-matrix interfaces critical to angiogenesis

... These researchers focused primarily on the chemical interactions between endothelial cells and pericytes, including the roles that basement membrane protein components [r] ...

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Cellulose-Pectin Spatial Contacts Are Inherent to Never-Dried Arabidopsis Primary Cell Walls: Evidence from Solid-State Nuclear Magnetic Resonance

Cellulose-Pectin Spatial Contacts Are Inherent to Never-Dried Arabidopsis Primary Cell Walls: Evidence from Solid-State Nuclear Magnetic Resonance

... Cellulose-Pectin Spatial Contacts Are Inherent to Never-Dried Arabidopsis Primary Cell Walls: Evidence from Solid-State Nuclear Magnetic Resonance The MIT Faculty has made this article openly available. ...

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The state against itself

The state against itself

... the state government can seek the collaboration of CSOs and make them actors in the policy process, and in the implementation and surveillance of development ...

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Collision-free state estimation

Collision-free state estimation

... the observation model parameters with the sample mean and covariance as before, but instead of performing local optimization, we simply generate samples from this joint Gaussian distribution and accept them if they are ...

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Revisiting cyanobacterial state transitions

Revisiting cyanobacterial state transitions

... during State II to State I transition (when photosys- tems move apart), concomitant with an increase in PSII fluo- rescence under the same ...in State II, which can be considered as an evidence for ...

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Syria: The Barbarian State

Syria: The Barbarian State

... agreement brokered by Moscow on the dismantling of Syria’s chemical arsenal indicated that only the use of unconventional weapons against the population was, in the end, prohibited. Majed ends his book with a lengthy ...

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Remarks on State denoting nominalizations

Remarks on State denoting nominalizations

... ‘The inquiry ignores that young people are idle’ c. *L’enquête ignore que le chômage désoeuvre les jeunes. ‘The inquiry ignores that unemployment makes young people idle’ Sentences (29a) and (30a) mean what sentences ...

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