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Cancer drugs

Decoupling market incumbency from organizational experience : a study of biotechnology's impact on the market for anti-cancer drugs

Decoupling market incumbency from organizational experience : a study of biotechnology's impact on the market for anti-cancer drugs

... of drugs related to cancer (406 ...anti-cancer drugs and drugs with low cross-elasticity of demand to cancer treatment ...beyond cancer treatment), I documented 146 ...

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in vivo analysis of Drosophila deoxyribonucleoside kinase function in cell cycle, cell survival and anti-cancer drugs resistance.

in vivo analysis of Drosophila deoxyribonucleoside kinase function in cell cycle, cell survival and anti-cancer drugs resistance.

... phylogeny, dNK belongs to the TK2, deoxycitidine kinase (dCK), deoxyguanosine kinase (dGK) and the Herpes viral thymidine kinase family, and is not so closely related to TK1. 6 The exact functions in vivo of the ...

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Ferrocifen type anti cancer drugs

Ferrocifen type anti cancer drugs

... In vivo studies have been performed with the 3 hits: Fc-diOH, Fc-OH-Tam and ansa- Fc-diOH. There were several challenges to succeed in the transfer from in vitro to in vivo experiments. The first one was to find a ...

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IGF1 receptor inhibition amplifies the effects of cancer drugs by autophagy and immune-dependent mechanisms−

IGF1 receptor inhibition amplifies the effects of cancer drugs by autophagy and immune-dependent mechanisms−

... of cancer, autophagy plays an ambiguous ...of cancer cells and allows them to avoid cell death induction in response to cytotoxicants or targeted ...pancreatic cancer, the induction of auto- phagy ...

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Applying System-Theoretic Accident Model Process view to patient safety for treatment with oral chemotherapy and anti-cancer drugs

Applying System-Theoretic Accident Model Process view to patient safety for treatment with oral chemotherapy and anti-cancer drugs

... The subject of the control structure is Dana-Farber's Oral Chemotherapy and Anti-Cancer treatment program, with a focus on patient safety. This result is shown in Figure [r] ...

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Screening anti-colorectal cancer drugs: free radical chemotherapy

Screening anti-colorectal cancer drugs: free radical chemotherapy

... CRC. Drugs were tested for 1 hour exposure as well as continuous exposure using standard clinical patient treatment ...12 drugs was also ...various drugs was observed (using a cut-off definition of ...

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Systematic assessment of multi-gene predictors of pan-cancer cell line sensitivity to drugs exploiting gene expression data

Systematic assessment of multi-gene predictors of pan-cancer cell line sensitivity to drugs exploiting gene expression data

... of cancer cell lines to anti-cancer drugs with generally high test set precision ( Figure 2 ), very poor precision and a very low recall was provided for other drugs, especially those that are ...

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The Comparative Effectiveness of Innovative Treatments for Cancer (CEIT-Cancer) project Rationale and design of the database and the collection of evidence available at approval of novel drugs

The Comparative Effectiveness of Innovative Treatments for Cancer (CEIT-Cancer) project Rationale and design of the database and the collection of evidence available at approval of novel drugs

... of cancer (for example, solid ...all cancer drugs, but none of them covers the most recently approved drugs (for example, after ...for cancer drugs is marked by not only a ...

14

A 3D model of ovarian cancer cell lines on peptide nanofiber scaffold to explore the cell–scaffold interaction and chemotherapeutic resistance of anticancer drugs

A 3D model of ovarian cancer cell lines on peptide nanofiber scaffold to explore the cell–scaffold interaction and chemotherapeutic resistance of anticancer drugs

... ovarian cancer is often an aggressive disease and is typically diagnosed at an advanced stage when thera- peutic resistance occurs, for reasons as yet ...ovarian cancer, which is still poorly understood, ...

9

Intradermal Tests With Drugs: An Approach to Standardization

Intradermal Tests With Drugs: An Approach to Standardization

... Barbaud et al. Standardization of Drug Intradermal Tests INTRODUCTION Allergy skin testing is essential for the correct diagnosis of immediate and delayed drug hypersensitivity (DH). It is also used to identify ...

9

Mucins and tumor resistance to chemotherapeutic drugs

Mucins and tumor resistance to chemotherapeutic drugs

... Mucins belong to a heterogeneous group of large O-glycoproteins that can be either secreted or membrane-bound. Implications of mucins have been described in relation to cancer cell behavior and cell signaling ...

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Biosynthetic engineering for the assembly of better drugs

Biosynthetic engineering for the assembly of better drugs

... To counter what had now become a clear and present danger from generic drug-makers, innovator pharmaceutical companies would adopt two paradigms that would eventuall[r] ...

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Delivery of drugs and biomolecules using carbon nanotubes

Delivery of drugs and biomolecules using carbon nanotubes

... an effective release of DOX, which enters the nucleus of can- cer cells and induces cell death. High degrees of p-stacking of DOX with an ultrahigh load- ing capacity is attached onto the water-soluble SWCNT, which are ...

22

Assessment of Cardiovascular Safety of Anti-Osteoporosis Drugs.

Assessment of Cardiovascular Safety of Anti-Osteoporosis Drugs.

... that interventions should be withheld whilst further informa- tion is gathered. The benefit/risk balance for MHT is most favourable in younger, recently postmenopausal women [ 58 , 59 ] (those who are less than 60 years ...

16

New inhibitors of quinolinate synthase as potential antibacterial drugs

New inhibitors of quinolinate synthase as potential antibacterial drugs

... Nicotinamide adenine dinucleotide (NAD) is an essential cofactor and substrate in numerous biological reactions. For this reason, both the enzymes that use it as a substrate and those participating on its biosynthetic ...

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Making rareness count: testing and pricing orphan drugs

Making rareness count: testing and pricing orphan drugs

... of drugs, and circulated amongst Member States, with an ultimate goal to sharing facts and figures on the value for money of orphan ...orphan drugs reveal the capacity of prices to serve as a problematizing ...

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Synapto-protective drugs evaluation in reconstructed neuronal network

Synapto-protective drugs evaluation in reconstructed neuronal network

... stability under pathological conditions range from whole animal models that preserve the anatomical structures but greatly limit experimentation at cell level, to dissociated cell culture systems that allow detailed ...

10

Insiders, smart drugs et pharmaceuticalisation : éléments pour une typologie de la nouvelle déviance
conformiste

Insiders, smart drugs et pharmaceuticalisation : éléments pour une typologie de la nouvelle déviance conformiste

... smart drugs : il consomme en solitaire, voire en secret, mais s’identifie et adhère à une pratique partagée à géométrie variable qu’il décrit comme raisonnablement répandue, voire banale et, en outre, dont les ...

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Access to antiretroviral drugs and AIDS management in Senegal

Access to antiretroviral drugs and AIDS management in Senegal

... In November 2000 the reduction in prices of antiretroviral drugs was immediately translated into a four-fold reduction in patients’ financial participation. The following year, 44% of newly enrolled patients ...

10

Polymeric micelles as versatile carriers for drugs and nucleic acids

Polymeric micelles as versatile carriers for drugs and nucleic acids

... deposition in the compromised vasculature of the pathological sites. This approach is currently under development by many research groups, with different PM formulations in different phases of clinical trial (Table 3) ...

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