Brite adipocytes
Visfatin expression analysis in association with recruitment and activation of human and rodent brown and brite adipocytes
... cold exposure or CL316,243 treatment. This is not related to brite adipocytes recruitment, as eWAT is less sensitive to these treatments and does not display high amounts of UCP1 positive cells. However, ...
26
Modulation of the inflammatory response to LPS by the recruitment and activation of brown and brite adipocytes in mice
... and (C) secreted leptin levels in plasma and subcutaneous white adipose tissue (scWAT). The 479[r] ...
30
Mitochondrial fission is associated with UCP1 activity in human brite/beige adipocytes
... brown adipocytes showed that the mitochondria acquired a round shape upon UCP1 activation ...white adipocytes displayed a mix of tubular and partially fragmented mitochondria (Figure 3a and ...contrast, ...
41
IP-receptor and PPARs trigger the conversion of human white to brite adipocyte induced by carbaprostacyclin
... white adipocytes into brite/beige adipocytes as shown by a strong expression of UCP1 ...white adipocytes in the presence of rosiglitazone from day 3 to day 9, as described in Materials and ...
28
Rôle des récepteurs nucléaires PPAR gamma et PPAR alpha dans la conversion d'adipocytes blancs humains en adipocytes bruns/brites
... white adipocytes can acquire these brown fat cell properties upon PPAR g or PPAR a ...and brite adipocytes compared to white fat cells, other markers have been identi fied in mouse studies to ...
287
Effet des acides gras polyinsaturés sur la conversion des adipocytes blancs en adipocytes brites
... Since brite/brown adipocytes appear absent from obese patients [8] , we therefore sought to analyze the possible role of u 6 ARA and its me- tabolites in human brown/brite adipocyte development and ...
223
Implication des microARNs dans la conversion des adipocytes blancs en adipocytes thermogéniques
... white adipocytes into brite adipocytes may lead to the development of novel therapeutic ...and brite adipocytes (49, ...of brite adipocyte development in mouse and human (46, ...
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Le recrutement et l’activation d’adipocytes bruns et/ou BRITE - Une perspective réelle pour le traitement des maladies métaboliques ?
... and/or BRITE adipocytes : potential therapeutic against metabolic diseases In mammals, typically two types of adipose tissues are described : the white and the brown adipose tissue (WAT and BAT ...brown ...
7
White-to-brite conversion in human adipocytes promotes metabolic reprogramming towards fatty acid anabolic and catabolic pathways
... thermogenic adipocytes within white adipose depots (so-called brown-in-white ...i.e., brite or beige adipocytes) protects from obesity and insulin ...resistance. Brite adipocytes may ...
15
All-trans retinoic acid induces oxidative phosphorylation and mitochondria biogenesis in adipocytes
... 3T3-L1 adipocytes ( 15 ...3T3-L1 adipocytes following ATRA exposure, necessary for both UCP1-dependent and UCP1-independent energy dissipation ...beige/ BRITE adipocytes) are readily induced ...
11
Ursolic acid inhibits Adipogenesis in 3T3-L1 Adipocytes through LKB1/AMPK pathway
... After 6-day differentiation in the presence of UA, 3T3-L1 adipocytes were collected and lysed in ice-cold RIPA lysis buffer for 30 minutes. Protein content was determined using a BCA protein assay kit. Equal ...
13
14-3-3zeta is required for PKA-dependent lipolysis in mature adipocytes
... Whereas a significant reduction in plasma glycerol levels was detected in male adi14-3-3ζKO mice injected with CL-316,243 (Figure 2A), there was no difference in plasma FFA levels between the adi14-3-3ζKO and control ...
91
Ursolic acid increases glucose uptake through the PI3K signaling pathway in adipocytes
... UA stimulates glucose uptake through regulating protein activities in the PI3K pathway To confirm the role of PI3K pathway in upregulating glucose uptake in adipocytes by UA, we further determined the expression ...
9
Secretion of a lysophospholipase D activity by adipocytes: involvement in lysophosphatidic acid synthesis.
... Abstract The aim of the present work was to depict the metabolic pathways involved in extra-cellular production of lysophosphatidic acid (LPA) by adipocytes. LPA was followed by quantifying the accumulation of ...
27
DNA damage and the activation of the p53 pathway mediate alterations in metabolic and secretory functions of adipocytes Running title: DNA damage and p53 in obese adipocytes
... 3T3-L1 adipocytes treated with doxorubicin or nutlin-3 revealed that among the expressed chemokines, eleven were deregulated in one or both experimental conditions ...
51
Hormonal Therapy Resistance and Breast Cancer: Involvement of Adipocytes and Leptin
... by adipocytes and cancer cells, they managed to decrease proliferation, migration, invasion, and EMT, suggesting the paracrine role of this adipokine [ 28 ...
17
Human Bone Marrow Is Comprised of Adipocytes with Specific Lipid Metabolism
... in vitro models. Mouse studies indicate that BM-Ad regulates he- matopoiesis and bone mass ( Naveiras et al., 2009; Zhou et al., 2017 ). However, the existence of species-specific differences between rodent and human ...
18
Regulation of chemokine and chemokine receptor expression by PPARG in adipocytes and macrophages
... Methodology and methods We used 3T3L1 mouse cells as a model of mature adipo- cytes. Conditioned media were prepared from 3T3L1 mature adipocytes exposed to different conditions and subsequently used for in vitro ...
3
Human immunodeficiency virus protease inhibitors accumulate into cultured human adipocytes and alter expression of adipocytokines.
... used adipocytes derived from adult stem (hMADS) cells isolated from human adipose ...into adipocytes. In adipocytes, amprenavir increased leptin expression and ritonavir was able to up-regulate tumor ...
8
Regulation of lipid metabolism in adipocytes and hepatocytes by hexarelin through scavenger receptor CD36
... (fasting). In a state of increased energy demand, glycogen synthesis is inhibited through the inhibition of its key enzyme, glycogen synthase (GS) by AMPK (Carling & Hardie, 1989). In addition, AMPK promotes the ...
300