Bone tumors
Antagonistic functions of connexin 43 during the development of primary or secondary bone tumors
... Keywords: gap junction; connexin 43; bone tumors; primary tumor growth; metastatic process 1. Gap Junction Channels According to Schleiden’s theory, cells are autonomous units circumscribed by a diffusion ...
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TRAIL receptor signaling and therapeutic option in bone tumors: the trap of the bone microenvironment.
... Concerning bone tumors, another level of regulation is added by the pres- ence and production by bone cells and MSC of OPG which is able to interact with ...the bone microenvironment and of ...
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New Insights about the Wnt/β-Catenin Signaling Pathway in Primary Bone Tumors and Their Microenvironment: A Promising Target to Develop Therapeutic Strategies?
... primary bone tumors mainly occurring in children, adolescents and young ...different bone tumors is their ability to deregulate bone homeostasis and remodeling and divert them to their ...
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Upscaling of fluid flow in spatially heterogeneous bone tumors
... malignant bone tumor that prefer- entially arises in adolescents and young ...of tumors exhibits strong spatial heterogeneities in terms of micro-architecture or differentiated response to treatments due to ...
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Upscaling of fluid flow in spatially heterogeneous bone tumors
... malignant bone tumor that prefer- entially arises in adolescents and young ...of tumors exhibits strong spatial heterogeneities in terms of micro-architecture or differentiated response to treatments due to ...
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miRNA-193a-5p repression of p73 controls Cisplatin chemoresistance in primary bone tumors
... The P73 gene is a member of the P53-related transcription factor family. It plays a crucial role during embryonic development and tumor progression, through mechanisms involving control of the genome stability and ...
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Receptor activator of nuclear factor-kappa B ligand (RANKL) stimulates bone-associated tumors through functional RANK expressed on bone-associated cancer cells?
... secondary bone tumors clearly deteriorate quality of life and the activity of daily living of ...secondary bone tumors develop in the unique bone tissue, it is therefore necessary to ...
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Does proliferation status predict radiation response in human tumors?
... Different assays are currently available: DNA pioidy and/or Tpot ~ e m s after bromo- or iododeoxy~dine pulse labelling assessed by flow cytomc'a'y, assessment of [r] ...
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Changes of Bone Turnover Markers in Long Bone Nonunions Treated with a Regenerative Approach
... therapy bone repair in everyday practice ...of bone healing, possibly at an early stage, is eagerly awaited by clinicians to predict treatment outcome, but cur- rently, there is no reliable way to predict ...
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Mouse Models Recapitulating Human Adrenocortical Tumors: What Is Lacking?
... signaling pathway cause adrenal hyperplasias and tumors. (1) Activating mutations of MC2R found in PBMAH patients lead to higher activation of the pathway. No mouse model is actually available for Mcr2 activating ...
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Progresses Toward Precision Medicine in RET -altered Solid Tumors
... ALK-rearranged tumors (ORR: 45% ...ALK-rearranged tumors, 114 respectively; ref. 22). RET-rearranged tumors tend to be mutually 115 exclusive with other major lung cancer drivers such as KRAS muta- ...
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Biocompatibility, bone healing, and safety evaluation in rabbits with an IlluminOss bone stabilization system
... INTRODUCTION Bone fracture stabilization with splints, casts, metal fixator plates, or intramedullary (IM) rods promote fracture healing by controlling bone movement and ...
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Jeu de pistes chez Betty Bone
... En 2010 paraît un album dont le titre s’inscrit verticalement sur la couverture, en référence à ce qu’il signifie : De haut en bas. Notre regard est aussitôt attiré par celui de la fillette dirigé vers le haut et le hors ...
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Deterministic Adjustable Bone Plate Design
... 3 Results A closed-form model with a fixed-fixed boundary condition indicates that a force of 292N is needed to deform the present plate adaptation. Numerical modeling results suggest a required force of 375N. Previous ...
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Phyto-oestrogens and bone health
... lished recently; one by the French Food Safety Agency (24) and one from the EU-funded project Phytohealth (31) . The comprehensive literature search with well-defined inclu- sion or exclusion criteria suggests, although ...
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Peripubertal female athletes in high-impact sports show improved bone mass acquisition and bone geometry
... for bone density, the bone geometry evaluated by HSA at the proximal femur was also modified according to the type of physical ...of bone geometry to high mechanical strain was demonstrated by higher ...
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HLA-B27 rats develop osteopaenia through increased bone resorption without any change in bone formation
... al.: Bone quality during spontaneous inflammatory bowel disease greater for HLA-B27 rats than for controls (Table ...Concerning bone parameters, femoral BMC was 22% lower in HLA-B27 than in control rats ...
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THYROID-RELATED BONE LESIONS : clinical illustration
... 2 Pediatrician endocrinologist, Pediatrics unit, CHR Citadelle, 4000 Liège INTRODUCTION : Primary hypothyroidism is a common endocrine disease. Although the diagnosis is often simple, some clinical presentations are ...
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Vitamin D: interest in non bone pathologies
... B-4000, Liège BELGIUM. The role of vitamin D (VTD) in maintaining bone health has been known for decades. Recently, however, the discovery that many tissues expressed the VTD receptor and were able to transform ...
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What bridges mineral platelets of bone?
... regarding this point seem to support Brown’s view and synthetic nanocrystalline apatites, free of carbonate ions, exhibit FTIR spectra close, although not identical, to that of OCP. 7 This hydrated surface structure ...
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