Bone Marrow Cells/pathology
Multi Features Based Approach for White Blood Cells Segmentation and Classification in Peripheral Blood and Bone Marrow Images
... blood cells into two classes in order to diagnose Myeloma ...plasma cells including normal and dystrophic cells, and the second class contains other white blood cells ...plasma cells ...
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Validation of Adult Bone Marrow Stromal Cells in Cellular Therapy Protocols, using a Mouse Model for Parkinson’s Disease
... Adult bone marrow stromal stem cells (BMSCs) have already been suggested as good candidates for cell therapy in CNS lesions, as those cells are multipotent (including the ability to ...
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The Chemokine Receptor CCR3 Is Potentially Involved in the Homing of Prostate Cancer Cells to Bone: Implication of Bone-Marrow Adipocytes
... 78 bone metastases from 45 castration resistant PCa patients and has been provided by the Prostate Cancer Biorepository Network ...includes bone metastasis from 13 patients and lymph node metastases from 11 ...
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CD4(+)CD25(+) regulatory T lymphocytes in bone marrow transplantation.
... epithelial cells are involved in thymic negative ...epithelial cells [7], autospecific T lymphocytes “escape” to the periphery and need to be kept under control by peripheral tolerance mechanisms ...
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Bone marrow-derived mesenchymal cells and MMP13 contribute to experimental choroidal neovascularization.
... BM-‐derived cells are sufficient to restore the vascularization impaired by Mmp13 ...BM-‐derived cells that contributed to the pathology in a model of liver fibrosis ...by bone marrow ...
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Induction of antigen-specific tolerance to bone marrow allografts with CD4+CD25+ T lymphocytes.
... The pathology can be prevented by injection of CD4 + CD25 + lymphocytes, which appear after day 3 of life in the peripheral lymphoid organs of normal ...T cells do not only inhibit autoimmunity; they can ...
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Bone marrow hematons: An access point to the human hematopoietic niche
... T cells in the spleen or BM could have been due to the engraftment of con- taminating mature cells in the injected human cell suspension (observed in HD10), the presence of CD4 1 CD8 1 and CD3 1 thymo- ...
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Mass cytometry deep phenotyping of human mononuclear phagocytes and myeloid-derived suppressor cells from human blood and bone marrow
... and bone marrow- derived MDSCs were determined in an allogeneic three-way mixed lymphocyte reaction (MLR) ...T cells were purified from PBMCs from a healthy donor using the Pan T Cell isolation kit ...
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Human Bone Marrow Is Comprised of Adipocytes with Specific Lipid Metabolism
... tracted from tissues and isolated adipocytes ( Figures S3 A and S3B). Quantitative liquid chromatography-tandem mass spectrometry (LC-MS/MS) of the total lipid content extracted from BM-Ads and SC-Ads was performed using ...
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Chitosan-collagen 3d matrix mimics trabecular bone and regulates rankl-mediated paracrine cues of differentiated osteoblast and mesenchymal stem cells for bone marrow macrophage-derived osteoclastogenesis
... culture cells in a three-dimensional (3D) matrix, since it gives the actual microenvironment, a similar structure to the biological ...for bone tissue ...how cells proliferate, differentiate, and ...
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Intraocular pressure reduction and neuroprotection conferred by bone marrow-derived mesenchymal stem cells in an animal model of glaucoma
... stem cells are both able to repopulate the degenerative TM and to acquire a TM cell morphology and phenotype to finally restore the TM filtrating prop- ...AC. Bone marrow-derived MSCs have also shown ...
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Adult Bone Marrow Neural Crest Stem Cells and Mesenchymal Stem Cells are not able to Replace Lost Neurons in Acute MPTP-lesioned Mice
... (45,9365,86 cells per representative mesencephalic plane, n = 5) and revealed a significant decrease (60%) of the number of cells compared to the control condition (129,40610,50 TH-positive neurons per ...
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Contribution of neuroblastoma-derived exosomes to the production of pro-tumorigenic signals by bone marrow mesenchymal stromal cells
... identified by NTA two peaks rich in particles, one at the top of the gradient (peak 1) and one in fraction 4 (peak 2, density of 1.05 g/ml). This second peak, designated odgcEVs, contained syntenin and ALIX in the ...
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Cellular and molecular immunotherapeutics derived from the bone marrow stroma
... Bone marrow-derived mesenchymal stem cells (MSCs) are an excellent candidate for cell-based therapy because: (1) bone marrow aspiration is a routine method used in medi[r] ...
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Enhanced human bone marrow mesenchymal stromal cell adhesion on scaffolds promotes cell survival and bone formation.
... cancellous bone graft is still until today the gold standard for regeneration of bone defects exceeding 4 cm [2] ...this bone transplantation approach has shown its clinical efficacy, it presents ...
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Persistence of Brucella abortus in the Bone Marrow of Infected Mice
... BM-infected cells were low at 8 (acute phase) and 30 (chronic phase) days of postinfection, suggest- ing that few infected cells harbored many bacteria (Figure ...some cells, a phenomenon that may ...
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The effects of dietary fatty acids on bone, hematopoietic marrow and marrow adipose tissue in a murine model of senile osteoporosis
... Hematopoietic bone marrow (HBM%), marrow adipose tissue (MAT%) and Bone (Bone%) volume fractions (Upper panel) and total marrow volume fractions of HBM and MAT compared between ...
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A Cellular Taxonomy of the Bone Marrow Stroma in Homeostasis and Leukemia
... vascular cells We identified three BMEC subsets each supported by distinct differentially expressed genes (Figure 5A,B, S5B and Table S1): cluster 0 consisted of putative sinusoidal BMECs, cluster 6 of ...
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en fr Antigen sensing by long-lived bone marrow IgM-expressing plasma cells Expression et fonction du récepteur antigénique B membranaire sur les plasmocytes médullaires producteurs d'IgM
... Autoreactive B cell receptors mimic autonomous pre-B cell receptor signaling and induce proliferation of early B cells.. Autophagy and the integrated stress response..[r] ...
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Bronchiolitis obliterans organizing pneumonia and ulcerative colitis after allogeneic bone marrow transplantation.
... To date, no case of transmission of inflammatory bowel disease from a marrow donor to its recipient has been reported. A case of typical ulcerative colitis following BMT has been reported (results of initial ...
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