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Beta-lactamase

Beta-lactamase database (BLDB) – structure and function

Beta-lactamase database (BLDB) – structure and function

... ABSTRACT Beta-Lactamase Database (BLDB) is a comprehensive, manually curated public resource providing up-to- date structural and functional information focused on this superfamily of enzymes with a great ...

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Extended-spectrum beta-lactamase − producing enterobacteriaceae in the intensive care unit: acquisition does not mean cross-transmission

Extended-spectrum beta-lactamase − producing enterobacteriaceae in the intensive care unit: acquisition does not mean cross-transmission

... extended-spectrum beta-lactamase − producing Enterobacteriaceae; ESBL: extended-spectrum beta-lactamase; ICU: intensive care unit; IGSII: index gravity score; IRB: institutional review board; ...

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Prevalence of extended-spectrum beta-lactamase producing Escherichia coli in community-onset urinary tract infections in France in 2013

Prevalence of extended-spectrum beta-lactamase producing Escherichia coli in community-onset urinary tract infections in France in 2013

... extended-spectrum beta-lactamase in Enterobacteriaceae has been associated with increased treatment failure and higher management ...extended-spectrum beta-lactamase producing Escherichia coli ...

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Émergence de souches de Salmonella Virchow multirésistantes et productrices d'une beta-lactamase à spectre étendu en Belgique en 2003

Émergence de souches de Salmonella Virchow multirésistantes et productrices d'une beta-lactamase à spectre étendu en Belgique en 2003

... D’UNE BETA-LACTAMASE A SPECTRE ETENDU EN BELGIQUE EN 2003 Introduction: L’émergence des souches de salmonelles multirésitantes représente un problème important tant en médecine humaine que pour la médecine ...

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First Detection of VIM-2 Metallo-beta-Lactamase-Producing Pseudomonas putida in Blattella germanica Cockroaches in an Algerian Hospital

First Detection of VIM-2 Metallo-beta-Lactamase-Producing Pseudomonas putida in Blattella germanica Cockroaches in an Algerian Hospital

... 5. Loucif L, Gacemi-Kirane D, Cherak Z, Chamlal N, Grainat N, Rolain J-M. 2016. First report of German cockroaches (Blattella germanica) as reser- voirs of CTX-M-15 extended-spectrum-beta-lactamase- and ...

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Presenec of extended-spectrum beta-lactamase-producing Enterobacteriaceae in the fecal flora of patients from general practice

Presenec of extended-spectrum beta-lactamase-producing Enterobacteriaceae in the fecal flora of patients from general practice

... extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-E) in the fecal flora of patients from general practice 18 th ECCMID Abstract 631 Cécile Meex 1 , Pierrette Melin 1 , Jean Denis Docquier ...

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Quantifying carriage of extended-spectrum beta-lactamase-producing enterobacteriaceae and subsequent ICU acquired infection in French Guiana

Quantifying carriage of extended-spectrum beta-lactamase-producing enterobacteriaceae and subsequent ICU acquired infection in French Guiana

... [29] Bonten MJ, Slaughter S, Ambergen AW, Hayden MK, van Voorhis J, Nathan C, et al. The role of “colonization pressure” in the spread of vancomycin-resistant enterococci: an important infection control variable. Arch ...

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2-Aminopropane-1,2,3-tricarboxylic acid: Synthesis and co-crystallization with the class A beta-lactamase BS3 of Bacillus licheniformis.

2-Aminopropane-1,2,3-tricarboxylic acid: Synthesis and co-crystallization with the class A beta-lactamase BS3 of Bacillus licheniformis.

... on the synthesis and the biochemical evaluation of potential inhib- itors of b-lactamases. Numerous b-lactamase inhibitors have been reported in the literature. 2 However, most of these drugs are b-lac- tam ...

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The 3-D structure of a zinc metallo-beta-lactamase from Bacillus cereus reveals a new type of protein fold

The 3-D structure of a zinc metallo-beta-lactamase from Bacillus cereus reveals a new type of protein fold

... The structure was solved by the multiple isomorphous replacement method, with density modification and phase combination, using X-ray data collected from the native.. protein and the T97[r] ...

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Correction to: Infection-related ventilator-associated complications in ICU patients colonised with extended-spectrum beta-lactamase-producing Enterobacteriaceae.

Correction to: Infection-related ventilator-associated complications in ICU patients colonised with extended-spectrum beta-lactamase-producing Enterobacteriaceae.

... Biostatistical and information system expertise: Jean-Francois Timsit (Medical and Infectious Diseases ICU, Bichat-Claude Bernard Hospital, Paris, France; UMR 1137 Inserm –Paris Didero[r] ...

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First occurrence of an IMP metallo-beta-lactamase in Aeromonas caviae: IMP-19 in an isolate from France.

First occurrence of an IMP metallo-beta-lactamase in Aeromonas caviae: IMP-19 in an isolate from France.

... manual, 3rd ed. Cold Spring Harbor Laboratory Press, Cold Spring Har- bor, NY. 16. Senda, K., Y. Arakawa, S. Ichiyama, K. Nakashima, H. Ito, S. Ohsuka, K. Shimokata, N. Kato, and M. Ohta. 1996. PCR detection of metallo- ...

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Dramatic broadening of the substrate profile of the Aeromonas hydrophila CphA metallo-beta-lactamase by site-directed mutagenesis

Dramatic broadening of the substrate profile of the Aeromonas hydrophila CphA metallo-beta-lactamase by site-directed mutagenesis

... From a B2 to a B3 Metallo-β-lactamase The Arg 121 residue is conserved in the BcII and CphA enzymes. Dal Peraro et al. (23) have shown by quantum chemistry calculations that, in the mono-zinc form of BcII, Arg 121 ...

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Consequences of Extended Spectrum Beta‐Lactamase–Producing Enterobacteriaceae and Methicillin‐Resistant Staphylococcus aureus Carriage in Awaiting Liver Transplant Patients

Consequences of Extended Spectrum Beta‐Lactamase–Producing Enterobacteriaceae and Methicillin‐Resistant Staphylococcus aureus Carriage in Awaiting Liver Transplant Patients

... We retrospectively included 250 of 483 cirrhotic placed on waitlist for LT from December 2015 to January 2018 in our liver transplant center at Pitié-Salpêtrière hospital, tha[r] ...

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Crystal structures of the Bacillus licheniformis BS3 class A beta-lactamase and of the acyl-enzyme adduct formed with cefoxitin

Crystal structures of the Bacillus licheniformis BS3 class A beta-lactamase and of the acyl-enzyme adduct formed with cefoxitin

... It is important to emphasize that in the BS3-cefoxitin structure, the R-methoxy group does not directly cause the conformational change but that it does so by influencing the 7β side chain orientation. In agreement with ...

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Discovery of novel lipophilic inhibitors of OXA-10 enzyme (class D beta-lactamase) by screening amino analogs and homologs of citrate and isocitrate.

Discovery of novel lipophilic inhibitors of OXA-10 enzyme (class D beta-lactamase) by screening amino analogs and homologs of citrate and isocitrate.

... C (P99 26 ), class D (OXA-10 27 ), and class B (BcII 28 , VIM-4 29 ). Class A enzymes are primarily penicillinases, susceptible to inhibition by the presently marketed -lactamase inhibitors, namely potassium ...

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X-ray analysis of the NMC-A beta-lactamase at 1.64-A resolution, a class A carbapenemase with broad substrate specificity

X-ray analysis of the NMC-A beta-lactamase at 1.64-A resolution, a class A carbapenemase with broad substrate specificity

... coding a mutant of the chromosomal ␤-lactamase of Kluyvera cryocrescens, was also identified at a plasmid location in E. cloacae 7506, suggesting the ISEcp1-assisted escape of bla KLUC from the chromosome. ...

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Role of Cys221 and Asn116 in the zinc-binding sites of the Aeromonas hydrophila metallo-beta-lactamase.

Role of Cys221 and Asn116 in the zinc-binding sites of the Aeromonas hydrophila metallo-beta-lactamase.

... * Measured as Ki. Measurements were done at 30 °C in 15 mM sodium cacodylate, pH 6.5. N.D., not determined. Mutation of Cys221 Cys221 was replaced by a Ser or an Ala residue. The purified proteins were analyzed by MS. ...

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Crystal structure of Enterobacter cloacae 908R class C beta-lactamase bound to iodo-acetamido-phenyl boronic acid, a transition-state analogue

Crystal structure of Enterobacter cloacae 908R class C beta-lactamase bound to iodo-acetamido-phenyl boronic acid, a transition-state analogue

... with aryl boronic acids were investigated. From the sta- tistical search with Relibase, apart from the structure of cocaine esterase in complex with phenyl boronic acid (PDB code 1JU3 [25]), aryl boronic acid ligands are ...

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Beta-lactamase-encoding gene identification by micro-arrays in phenotypically resistant pathogenic Escherichia coli from young calves in Wallonia, Belgium.

Beta-lactamase-encoding gene identification by micro-arrays in phenotypically resistant pathogenic Escherichia coli from young calves in Wallonia, Belgium.

... Objectives Since 2012, a decrease of β-lactam resistance of pathogenic Escherichia (E.) coli from calves has been observed at ARSIA, the Regional Veterinary Diagnostics laboratory in Wallonia, Belgium. This may be a ...

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The two beta-lactamase genes of Streptomyces cacaoi, blaL and blaU, are under the control of the same regulatory system.

The two beta-lactamase genes of Streptomyces cacaoi, blaL and blaU, are under the control of the same regulatory system.

... Bartowsky E, Normark S (1993) Interactions of wild-type and mutant AmpR of Citrobacter freundii with target DNA. Mol Microbiol 10:555±565 Bennett PM, Chopra I (1993) Molecular basis of b-lactamase in- duction in ...

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