Beta cells
Role of microRNAs and their machinery in hepatocytes and pancreatic beta cells
... main beta cell mission consists in its ability to secrete insulin for maintenance of organismal glucose ...Indeed, beta cells have a dedicated metabolism comprised of a tightly regulated chain of ...
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Proteasome dysfunction mediates high glucose-induced apoptosis in rodent beta cells and human islets
... in beta cell apoptosis in glucotoxic conditions, and to evaluate whether such a dysfunction might be pharmacologically ...INS-1E beta cells or human islets after high glucose and/or UPS inhibitor ...
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Horizontal transfer of exosomal microRNAs transduce apoptotic signals between pancreatic beta-cells
... Quantification of mature miRNA levels Expression of mature miRNAs was quantified with the miRCURY LNA TM Universal RT microRNA PCR kit (Exiqon). Briefly, 200 ng of exosomal or cellular RNAs were used for reverse ...
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Quercetin induces insulin secretion by direct activation of L-type calcium channels in pancreatic beta cells
... Introduction Plant foods contain flavonoids, polyphenolic compounds with protective effects in several chronic diseases. One of the most widely distributed flavonoids in the human diet, quer- cetin ...
13
Differential usage of NF-kB activating signals by IL-1b and TNF-a in pancreatic beta cells
... 2.4. Western blot assay Total or immunoprecipitated protein extracts were obtained from cells after exposure to treatment and/or transfection with specific siRNA [5,7] . Proteins were fractioned in a 10% SDS–PAGE ...
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Guiding pancreatic beta cells to target electrodes in a whole-cell biosensor for diabetes
... islet cells Cells from 100 mouse islets were seeded into 1-well ...of cells was evaluated by recording their response to glucose and various drugs and subsequently ana- lyzed ...electrophoresed ...
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The intermediate proteasome is constitutively expressed in pancreatic beta cells and upregulated by stimulatory, low concentrations of interleukin 1 β
... β cells is broken, with proinsulin serving as a major ...immune cells [ 32 , 33 ...β cells by inflammatory cytokines is of high interest and therapeutic ...
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Progenitor potential of nkx6.1-expressing cells throughout zebrafish life and during beta cell regeneration.
... its beta cells following their selective destruction ...ductal cells, such as CACs, behave as pancreatic progenitors/stem cells in normal – non-diabetic – adult animals and during regeneration ...
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Cooperative deformation of hydrogen bonds in beta-strands and beta-sheet nanocrystals
... given by E hb = D hb 关5共R hb /R DA 兲 12 − 6共R hb /R DA 兲 10 兴cos 4 共 DHA 兲, 共7兲 where D hb has the physical meaning as the depth of the H-bond energy and R hb as the zero force distance for the H bond if cos共 DHA 兲 ...
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Enhancement of genomic instability by 17[beta]-estradiol in minisatellite sequences of X-ray-transformed mouse 10T1/2 cells
... Our results demonstrate that 17P-estradiol highly enhances the onset of genomic rearrangement, a type of genomic instability, in malignant clones of mouse IOTV2 cells, while the genome o[r] ...
6
Tilings for Pisot beta numeration
... associated with beta numeration. It is well known that they induce an aperiodic multiple tiling of their representation space, and there are several topological, combinatorial, and arithmetical conditions that ...
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Evaluating the potential of poly(beta-amino ester) nanoparticles for reprogramming human fibroblasts to become induced pluripotent stem cells
... Figure 3 Flow cytometry data for IMR-90 cells transfected with EGFP using the leading polymers. Transfection efficacy expressed as percent green fluorescent protein- positive live cells (A) following a ...
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The role of transforming growth factor-beta 1 in steroidogenesis, cell proliferation, and apoptosis in cultured bovine granulosa cells
... Title: Transforming growth factor-~ 1 inhibits luteinization and promotes apoptosis in bovine granulosa cens ... TGF -~ 1 influence on steroidogenesis in cultured bovine gra[r] ...
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The CCAAT/Enhancer-Binding Protein Beta-2 Isoform (CEBPbeta-2) Upregulates Galectin-7 Expression in Human Breast Cancer Cells
... Transient transfection and luciferase assay Vectors encoding human C/EBPa or b (SC303472 and SC319561; Origene, Burlington, ON) and vectors encoding C/ EBPb-2 and C/EBPb-3 (No. 15738 and No. 15737; Addgene, Cambridge, ...
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Calculation of beta spectral shapes
... of beta decays are often needed, especially when measurements are carried out using Liquid Scintillation Counting, since the mod- eling of the light emission used in the triple to double coinci- dence ratio (TDCR) ...
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BETADAT: A Beta Cephei Database
... Soon available: graphical tool to plot the results in the HR diagram.. BetaDat: A Cephei Database[r] ...
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Permutations and negative beta-shifts
... Elizalde [5] ex- tended this study to β-shifts (with β > 1), and he determined for each permutation the infimum of those bases β where successive elements of the β-shift are ordered a[r] ...
4
Permutations and negative beta-shifts
... [8] S. Ito and T. Sadahiro, Beta-expansions with negative bases, Integers 9 (2009) A22, 239–259. [9] L. Liao and W. Steiner, Dynamical properties of the negative beta-transformation, Ergodic Theory Dynam. ...
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Peptidase Activity of Beta-Lactamases
... The rate of the acylation reaction is thus influenced by the nature of the leaving group, as demonstrated by a comparison of the k cat \K m values of similar peptides, esters and S-ester[r] ...
5
Etude de la decroissance beta+ des noyaux 185,187 Au
... site d'émission. ,dans un détecteur-de petite taille, il se peut qu'une grande partie .de cette radiation s'échappe, affectant considérablement les caractéristiques de [r] ...
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