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Plasmodium falciparum resistance to artemisinin-based combination therapies: A sword of Damocles in the path toward malaria elimination

Plasmodium falciparum resistance to artemisinin-based combination therapies: A sword of Damocles in the path toward malaria elimination

... Introduction Malaria is widespread in countries located in tropical and sub-tropical regions, where an estimated 3.2 billion people, nearly half of the world ’s population, are at risk of infection [ 79 ]. Among the five ...

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Treatment of malaria from monotherapy to artemisinin-based combination therapy by health professionals in rural health facilities in southern Cameroon

Treatment of malaria from monotherapy to artemisinin-based combination therapy by health professionals in rural health facilities in southern Cameroon

... Conclusion: The present study indicates that AS/AQ was not available in the public health facilities at the time of the study, and health practitioners were not informed about the new treatment guidelines. Results of ...

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Molecular monitoring of plasmodium falciparum drug susceptibility at the time of the introduction of artemisinin-based combination therapy in Yaoundé, Cameroon: Implications for the future

Molecular monitoring of plasmodium falciparum drug susceptibility at the time of the introduction of artemisinin-based combination therapy in Yaoundé, Cameroon: Implications for the future

... Then, artemisinin-based combination therapy (ACT), notably artesunate-amodiaquine (AS-AQ) or artemether-lumefantrine (AL), was gradually introduced in ...

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Repeated Artemisinin-Based Combination Therapies in a Malaria Hyperendemic Area of Mali: Efficacy, Safety, and Public Health Impact

Repeated Artemisinin-Based Combination Therapies in a Malaria Hyperendemic Area of Mali: Efficacy, Safety, and Public Health Impact

... Malaria Research and Training Center, Department of Epidemiology of Parasitic Diseases, Faculty of Medicine, Pharmacy and Odonto-Stomatology, University of Bamako, Bamako, Mali; Aix-Marseille University, Marseille, ...

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Low use of artemisinin-based combination therapy for febrile children under five and barriers to correct fever management in Benin: a decade after WHO recommendation

Low use of artemisinin-based combination therapy for febrile children under five and barriers to correct fever management in Benin: a decade after WHO recommendation

... possible. Artemisinin-based combination ther- apy (ACT) is used for the treatment of malaria cases in areas where Plasmodium species are resistant to certain anti-malarial ...provided based on the ...

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China and the circulation of artemisinin-based malaria treatment in the Comoros Union

China and the circulation of artemisinin-based malaria treatment in the Comoros Union

... of artemisinin (青蒿素) to Tu Youyou in October 2015 was remarkable in at least two ways: first, never before has a development emerging from traditional Chinese medicine been recognized with such an important award, ...

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Treatment of malaria from monotherapy to artemisinin-based combination therapy by health professionals in urban health facilities in Yaoundé, central province, Cameroon

Treatment of malaria from monotherapy to artemisinin-based combination therapy by health professionals in urban health facilities in Yaoundé, central province, Cameroon

... to artemisinin-based combination therapy ...(ii) artemisinin derivatives should not be given to pregnant women during the first trimester of gestation and quinine remained the recommended treatment ...

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Lack of artemisinin resistance in Plasmodium falciparum in northwest Benin after 10 years of use of artemisinin-based combination therapy

Lack of artemisinin resistance in Plasmodium falciparum in northwest Benin after 10 years of use of artemisinin-based combination therapy

... Benin, artemisinin-based combination therapy (ACT) has been recommended as the first-line treatment for uncomplicated Plasmodium falciparum malaria since ...

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A new geography of pharmaceuticals : Trajectories of artemisinin-based medicines

A new geography of pharmaceuticals : Trajectories of artemisinin-based medicines

... promising artemisinin derivatives: artesunate and ...several artemisinin-based drugs that are registered in China, so WHO’s goal is to bring Chinese laboratories and factories in line with ...

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High-level artemisinin-resistance with quinine co-resistance emerges in P. falciparum malaria under in vivo artesunate pressure

High-level artemisinin-resistance with quinine co-resistance emerges in P. falciparum malaria under in vivo artesunate pressure

... on artemisinin derivatives for both the treatment and control of malaria, with few alternatives ...during artemisinin-based combination therapy has established in Southeast Asia, and is emerging ...

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Design, Synthesis and Efficacy of Hybrid Triclosan‐gold Based Molecules on Artemisinin‐resistant Plasmodium falciparum and Leishmania infantum Parasites

Design, Synthesis and Efficacy of Hybrid Triclosan‐gold Based Molecules on Artemisinin‐resistant Plasmodium falciparum and Leishmania infantum Parasites

... of artemisinin and its derivatives contributed to the notable decrease of malaria mortality for the 20 last ...combining artemisinin derivatives with one or two other antimalarial drugs having different ...

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Constraint-based reachability

Constraint-based reachability

... Several authors have advocated the usage of constraints to represent an infinite set of states and the usage of constraint solvers to efficiently address reachability problems [6, 13, 16, 4]. In automated program ...

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Template Based MDE

Template Based MDE

... Template Based Model Engineering In this modeling space, designers of model templates are mainly concerned with “design for reuse” and the constitution of libraries (“o↵-the-shelf ...

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Making artemisinin

Making artemisinin

... / La version de cette publication peut être l’une des suivantes : la version prépublication de l’auteur, la version acceptée du manuscrit ou la version de l’éditeur. For the publisher’[r] ...

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DTM-based Filtrations

DTM-based Filtrations

... Contributions. In this paper, we introduce and study a new family of filtrations based on the notion of DTM. Our contributions are the following: Given a set X ⊂ R d , a weight function f defined on X and p ∈ [1, ...

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Bio-based paints

Bio-based paints

... Additives are compounds used in low concentrations (a few percent), whose function is to either promote or prevent some developments of the product. For example, surfactants improve the homogeneity of the dispersion. ...

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Property Based Coordination

Property Based Coordination

... The latter embeds the non-agent entities. With the observable properties, the entities composing the environment can be clustered into agent categories, messages typology etc. which can be available as meta-information ...

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A Motion-Based Feature for Event-Based Pattern Recognition

A Motion-Based Feature for Event-Based Pattern Recognition

... Indeed the method in Clady et al. (2015) requires to memorize the stream of the visual motion events (see Equation 2) and spatiotemporal extrapolations of them (called “normal events”) and operates quite complex ...

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Query-based Comparison of Mappings in Ontology-based Data Access

Query-based Comparison of Mappings in Ontology-based Data Access

... In addition, the OBDA specification plays a major role in query answering, since its form may affect the system per- formance in answering queries: different, yet semantically equivalent specifications may give rise to ...

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