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Antigen-presenting cells (APC)

Minimum information about tolerogenic antigen-presenting cells (MITAP): a first step towards reproducibility and standardisation of cellular therapies

Minimum information about tolerogenic antigen-presenting cells (MITAP): a first step towards reproducibility and standardisation of cellular therapies

... living cells shows great promise for the treatment of a wide variety of complex ...myeloid antigen-presenting cells (APC) with immunoregulatory function to treat autoimmune diseases, or to ...

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Plasmodium falciparum exposure in utero, maternal age and parity influence the innate activation of foetal antigen presenting cells.

Plasmodium falciparum exposure in utero, maternal age and parity influence the innate activation of foetal antigen presenting cells.

... that antigen presenting cells (APC), such as monocytes and dendritic cells (DC), contribute to the modulation of foetal immune responses upon exposure to ...of cells; myeloid DC (MDC) ...

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Letters to the Editor: Correspondence re R. Lapointe et al., CD40-stimulated B Lymphocytes Pulsed with Tumor Antigens Are Effective Antigen-presenting Cells That Can Generate Specific T Cells. Cancer Res 2003;63:2836–43.

Letters to the Editor: Correspondence re R. Lapointe et al., CD40-stimulated B Lymphocytes Pulsed with Tumor Antigens Are Effective Antigen-presenting Cells That Can Generate Specific T Cells. Cancer Res 2003;63:2836–43.

... CD40-B cells generate tumor antigen-specific CD4 ⫹ T cells in cancer patients when the B cells are pulsed with lysate from tumor cells ...CD40-B cells as ...

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Lymphotoxin α fine-tunes T cell clonal deletion by regulating thymic entry of antigen-presenting cells

Lymphotoxin α fine-tunes T cell clonal deletion by regulating thymic entry of antigen-presenting cells

... of antigen-presenting cells Noëlla Lopes 1 , Jonathan Charaix 1 , Oriane Cédile 2 , Arnauld Sergé 3 & Magali Irla 1 Medullary thymic epithelial cells (mTEC) purge the T cell repertoire of ...

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CD40-stimulated B Lymphocytes Pulsed with Tumor Antigens Are Effective Antigen-presenting Cells That Can Generate Specific T Cells

CD40-stimulated B Lymphocytes Pulsed with Tumor Antigens Are Effective Antigen-presenting Cells That Can Generate Specific T Cells

... as antigen-presenting cells, the role of antigen-unspecific B lymphocytes in antigen presentation and T-lympho- cyte stimulation remains ...B cells to stimulate T cells ...

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Anti-Gal-mediated targeting of human B lymphoma cells to antigen-presenting cells: a potential method for immunotherapy using autologous tumor cells.

Anti-Gal-mediated targeting of human B lymphoma cells to antigen-presenting cells: a potential method for immunotherapy using autologous tumor cells.

... lymphoma cells even after 24 hours of incubation of these cells at ...lymphoma cells will be lethally irra- diated prior to vaccination, in order to prevent in vivo proliferation of the tumor ...

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Ito Cells Are Liver-Resident Antigen-Presenting Cells for Activating T Cell Responses

Ito Cells Are Liver-Resident Antigen-Presenting Cells for Activating T Cell Responses

... Ito Cells Express CD1 Molecules and APC Surface Markers In order to investigate the impact of Ito cells on NKT cells, we isolated Ito cells from liver of C57BL/6 mice via the pro- nase and ...

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en fr Study of HIV-1 transfer from antigen presenting cells to primary CD4 T lymphocytes and inhibition by neutralizing antibodies Etude du transfert du VIH-1 des cellules présentatrices d'antigènes aux lymphocytes T CD4 primaires et inhibition par les anticorps neutralisants

... Infection of specific dendritic cells by CCR5-tropic human immunodeficiency virus type 1 promotes cell-mediated transmission of virus resistant to broadly neutralizing antibodies.. Gan[r] ...

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Nano-clustering of ligands on surrogate antigen presenting cells modulates T cell membrane adhesion and organization

Nano-clustering of ligands on surrogate antigen presenting cells modulates T cell membrane adhesion and organization

... Mem-GFP cells as control, in order to account for possible bias in TIRFM imaging arising from membrane ...Mem-GFP cells, as observed in TIRFM, exhibit large but poorly contrasted patches which are seen to ...

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Mechanism of action and recruitment of antigen-presenting cells in a mouse model of multiple sclerosis

Mechanism of action and recruitment of antigen-presenting cells in a mouse model of multiple sclerosis

... The microarray data from IL-6 treated bEnd.3 mouse cerebral endothelial cell line and tissue validation by mRNA quantification results obtained from WT→WT and WT→IL-6Rα fl/fl Tie2 cre mice revealed CXCL1 and PTGS2 ...

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Mechanics of antigen extraction by B cells

Mechanics of antigen extraction by B cells

... B cells produce antibodies and are therefore essential effectors of adaptive ...neighboring antigen presenting ...B cells to extract and process ...B cells: (1) Membrane spreading ...

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CD8[superscript +] T-cell Responses Rapidly Select for Antigen-Negative Tumor Cells in the Prostate

CD8[superscript +] T-cell Responses Rapidly Select for Antigen-Negative Tumor Cells in the Prostate

... + cells continue to grow within the tumor ...tumor cells in TRP-SIY mice prior to T cell treatment further suggests that the outgrowth of Tag + SIY - tumor cells compromised the efficacy of 2C T cell ...

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Anthrax Protective Antigen Retargeted with Single‐Chain Variable Fragments Delivers Enzymes to Pancreatic Cancer Cells

Anthrax Protective Antigen Retargeted with Single‐Chain Variable Fragments Delivers Enzymes to Pancreatic Cancer Cells

... mPA-scFv fusions efficiently translocate a toxin-derived reporter to the cellular cytosol. The enzyme DTA (catalytic A chain of diphtheria toxin) inhibits protein synthesis via ADP-ribosylation of eukaryotic elongation ...

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Antigen-specific B-cell receptor sensitizes B cells to infection by influenza virus

Antigen-specific B-cell receptor sensitizes B cells to infection by influenza virus

... B cells with a BCR specific for the HA of A/WSN/33 (FluBI ...B cells secrete an IgG2b that neutralizes infectious virus. While B cells from FluBI and control mice bind equivalent amounts of virus ...

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ABCG2, a novel antigen to sort luminal progenitors of BRCA1- breast cancer cells.

ABCG2, a novel antigen to sort luminal progenitors of BRCA1- breast cancer cells.

... stem cells express transmem- brane transporters, including ...the cells and as such, behaves as one of the major mediators of side population ...stem cells from different organs and species ...SP ...

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A high-throughput method for characterizing novel chimeric antigen receptors in Jurkat cells

A high-throughput method for characterizing novel chimeric antigen receptors in Jurkat cells

... and cells expressing EGFRvIII as antibodies ( Fig- ure S2 ...Jurkat cells were electropo- rated, seeded in 96-well plates, and co-cultured with varying numbers of U87 or EGFRvIII-expressing U87-vIII ...

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Expression of Viral Antigen by the Liver Leads to Chronic Infection Through the Generation of Regulatory T Cells

Expression of Viral Antigen by the Liver Leads to Chronic Infection Through the Generation of Regulatory T Cells

... In addition to their classic roles of maintaining immu- nologic tolerance to self and preventing autoimmunity, CD4 þ regulatory T cells can also inhibit immune responses against pathogens. In HCV infection, the ...

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Antigen-Bearing Dendritic Cells Regulate the Diverse Pattern of Memory CD8 T Cell Development in Different Tissues

Antigen-Bearing Dendritic Cells Regulate the Diverse Pattern of Memory CD8 T Cell Development in Different Tissues

... of Antigen-Bearing Dendritic Cells over Time and in Different Tissues Following Influenza Virus ...of antigen-bearing DCs in NDLN, DLN, and spleen in CD11c-DTR/EGFP transgenic mice, in which CD11c + ...

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Presenting the Gender and Health Research Group

Presenting the Gender and Health Research Group

... Nevertheless, the part devoted to societal challenges appears only in a few pages of the third section of the document which reports the evolution in knowledge on [r] ...

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