Antibody response
IgA dominates the early neutralizing antibody response to SARS-CoV-2
... serum-specific antibody ti- ters (Figure S5H), suggesting that a part of the SARS-CoV-2 antibody response is generated ...in response to infection with ...
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The antibody response to Plasmodium falciparum : cues for vaccine design and the discovery of receptor-based antibodies
... robust antibody responses against merozoite antigens, and the breadth of this antibody response has been associated with protection against clinical malaria ...monoclonal antibody that bound ...
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A DNA-Modified Live Vaccine Prime–Boost Strategy Broadens the T-Cell Response and Enhances the Antibody Response against the Porcine Reproductive and Respiratory Syndrome Virus
... xenogeneic antibody [ 52 ]. Indeed, the xenogeneic antibody sequences, here represented by mouse scFv, are presumably intrinsically immunogenic in the pig and the anti-scFv response mounted by the ...
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The CARD8 p.C10X mutation associates with a low anti-glycans antibody response in patients with Crohn's disease.
... lower antibody response with respect to glycans which are present on the surface of ...for antibody response directed against chitin, a wide spread component, highlighting a difference in ...
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Ebola vaccine development: Systematic review of pre-clinical and clinical studies, and meta-analysis of determinants of antibody response variability after vaccination
... of antibody response variability in humans that remained unex- plained by the factors included in the ...with antibody response after preventive vaccination against EVD: the Ebola vaccine ...
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Antibody Response to Toscana Virus and Sandfly Fever Sicilian Virus in Cats Naturally Exposed to Phlebotomine Sand Fly Bites in Portugal
... al. Antibody response to Phlebotomus perniciosus saliva in cats naturally exposed to phlebotomine sand flies is positively associated with Leishmania ...
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Evaluation of the Human IgG Antibody Response to Aedes albopictus Saliva as a New Specific Biomarker of Exposure to Vector Bites
... of exposure in a given population living in the same area can obviously vary between individuals, these results suggest that the anti-SGE IgG response may be a reliable biomarker for exposure to Ae. albopictus ...
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First Attempt To Validate Human IgG Antibody Response to Nterm-34kDa Salivary Peptide as Biomarker for Evaluating Exposure to Aedes aegypti Bites
... IgG response was compared between the dry and the rainy seasons for both years, taking into account the peak of the dry (February) and the rainy (July) ...Ab response to whole saliva in human populations ...
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Human IgG antibody response to Aedes Nterm-34kDa salivary peptide, an epidemiological tool to assess vector control in Chikungunya and Dengue transmission area
... Ab response to ...Ab response to the Nterm-34kDa peptide was detected in ...Ab response to only one antigen (antigenic peptide) instead of overall antigenic proteins contained in the ...Ab ...
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Modeling the antibody response : from the structure of immunoglobulins - antigen complexes to the clonal complexity of heavy chain repertoires
... “Predicting binding poses and affinities for protein - ligand complexes in the 2015 D3R Grand Challenge using a physical model with a statistical parameter estimation”. Journal of comput[r] ...
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en fr Study of the neutralizing antibody response against the hepatitis C virus Etude de la réponse humorale neutralisante contre le Virus de l’Hépatite C
... Dans un premier temps nous avons étudié l inhibition de l entrée et la capacité de neutralisation in vitro de l anticorps D Pour cela nous avons développé un test de cell b[r] ...
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Antibody evasion by a gammaherpesvirus o-glycan shield.
... immune response induced in the rabbits by the Bo10 STOP strain to that observed with the wild type parental strain (Figure ...anti-BoHV-4 antibody response was observable between the groups of ...
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Determining the Phagocytic Activity of Clinical Antibody Samples
... an antibody sample from an HIV negative subject (black trace) and an HIV positive subject (gray ...control antibody (triangle) demonstrates no phagocytic ...
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Compromised SARS-CoV-2-specific placental antibody transfer
... across antibody populations, multivariate dimensionality reduction was coupled to multivariate visualiza- tion, using Elastic Net regularization and feature reduction with multi-level orthogonal partial ...
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Multispecific Antibody Development Platform Based on Human Heavy Chain Antibodies
... immune response is functioning as expected is that antigen-specific UniAbs show comparable somatic hypermutation rates to light chain containing antibodies derived using similar immunization strategies ( 22 ...
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Application of Assisted Design of Antibody and Protein Therapeutics (ADAPT) improves efficacy of a Clostridium difficile toxin a single-domain antibody
... Owing to the importance of ainity maturation to biologics optimization, we have recently devised ADAPT (Assisted Design of Antibody and Protein Therapeutics), a platform that interleave[r] ...
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The Complement System and Antibody-Mediated Transplant Rejection
... DSA assays that measure complement binding/activation To improve the ability of solid-phase assays to predict allograft injury, the single antigen bead assay has been modified to measure complement activation by DSA ...
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Peptide-Based Vaccination for Antibody Responses Against HIV
... 55. Ringel, O.; Müller, K.; Koch, J.; Brill, B.; Wolf, T.; Stephan, C.; Vieillard, V.; Debré, P.; Dietrich, U. Optimization of the EC26-2A4 Epitope in the gp41 Membrane Proximal External Region Targeted by Neutralizing ...
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Antibody complementarity determining region design using high-capacity machine learning
... We demonstrated that we can combine machine learning models to reject antibodies that bind undesired targets to improve antibody specificity, a key property for therapeutic safety. Importantly, Fig. 5. ...
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An update on antibody-based immunotherapies for Clostridium difficile infection
... next-generation antibody therapeutics with improved and more complete ...A/B antibody combinations are in the early stages of development and claim to have improved preclinical efficacy in reducing CDI ...
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