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anti-tumor

Protein Kinase C-θ (PKC-θ) in Natural Killer Cell Function and Anti-Tumor Immunity.

Protein Kinase C-θ (PKC-θ) in Natural Killer Cell Function and Anti-Tumor Immunity.

... efficient anti-tumor immune ...of tumor cells with reduced or absent major histocompatibility complex class-I (MHC-I) ...in anti-tumor immunotherapy in the ...cell-mediated ...

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Intestinal Microbiota: A Novel Target to Improve Anti-Tumor Treatment?

Intestinal Microbiota: A Novel Target to Improve Anti-Tumor Treatment?

... on tumor-bearing mice focused on the role played by the gut microbiota on CTX ...impaired tumor regression in GF mice and in antibiotic-treated mice concomitantly to a reduced CTX-induced Th17 cell ...

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Serological markers for prediction of response to anti-tumor necrosis factor treatment in Crohn's disease

Serological markers for prediction of response to anti-tumor necrosis factor treatment in Crohn's disease

... monoclonal anti-tumor necrosis factor (TNF) antibodies (infliximab, Remicade) is a new therapeutic approach for severe refractory luminal or fistulizing, Crohn's disease ...to anti-TNF have been ...

7

Severe skin lesions cause patients with inflammatory bowel disease to discontinue anti-tumor necrosis factor therapy.

Severe skin lesions cause patients with inflammatory bowel disease to discontinue anti-tumor necrosis factor therapy.

... The anti-TNF agents are globally safe 6 although some concerns have been raised regarding an increased risk of opportunistic infections 7 and lymphoproliferative diseases 8 in a small percentage of ...with ...

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The humanized anti-human AMHRII mAb 3C23K exerts an anti-tumor activity against human ovarian cancer through tumor-associated macrophages

The humanized anti-human AMHRII mAb 3C23K exerts an anti-tumor activity against human ovarian cancer through tumor-associated macrophages

... of tumor cells was statistically and significantly decreased from the first day of treatment with ...3C23K. Anti-tumor effects were neither seen in presence of the irrelevant mAb R565 nor in the ...

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Anti-NKG2D single domain-based antibodies for the modulation of anti-tumor immune response

Anti-NKG2D single domain-based antibodies for the modulation of anti-tumor immune response

... by tumor cells such as down-regulation or shedding of ...in anti-tumor ...of anti- tumor antibodies targeting a tumor-associated antigen has been used to artificially enhance the ...

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Selection of a suitable disc bioassay for the screening of anti-tumor molecules

Selection of a suitable disc bioassay for the screening of anti-tumor molecules

... screening anti-tumor ...the anti-tu- mor screening test. In fact, maximal tumor induction was observed on beet discs ...of anti-tumor molecules in mammalian ...

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Intestinal Microbiota: A Novel Target to Improve Anti-Tumor Treatment?

Intestinal Microbiota: A Novel Target to Improve Anti-Tumor Treatment?

... on tumor-bearing mice focused on the role played by the gut microbiota on CTX ...impaired tumor regression in GF mice and in antibiotic-treated mice concomitantly to a reduced CTX-induced Th17 cell ...

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Plasticity of gammadelta T Cells: Impact on the Anti-Tumor Response

Plasticity of gammadelta T Cells: Impact on the Anti-Tumor Response

... cytokines, anti-tumor response, pro-tumor response INTRODUCTION Cancer initiation, progression, and invasion rely on the active com- munication between cancer cells and the different cell types in ...

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18 F-labeled analogues of anti-tumor agent calixarene 0118

18 F-labeled analogues of anti-tumor agent calixarene 0118

... of anti-tumor agent calix[4]arene 0118 containing a terminal alkyne functional group, successfully developed a multi-step synthetic strategy for their preparation, and optimized radiolabeling conditions for ...

1

The Janus face of immunity how anti-tumor immunity leads to autoimmunity in paraneoplastic neurological diseases

The Janus face of immunity how anti-tumor immunity leads to autoimmunity in paraneoplastic neurological diseases

... Thus, the collective effect of TRAIL, FasL, and perforin, and the increased expression of MHC class I molecules, underlies some of the molecular tools by which effector CD8+ T cells dire[r] ...

207

The androgen receptor independent mechanism of toxicity of the novel anti-tumor agent 11[beta]-dichloro

The androgen receptor independent mechanism of toxicity of the novel anti-tumor agent 11[beta]-dichloro

... We decided to investigate whether the induction of the UPR and sterol biosynthesis pathways by 11p -dichloro is specific for LNCaP cells, or they are more general cellular[r] ...

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Anti-tumor efficacy of hyaluronan-based nanoparticles for the co-delivery of drugs in lung cancer

Anti-tumor efficacy of hyaluronan-based nanoparticles for the co-delivery of drugs in lung cancer

... inhibit tumor growth and was well ...lung tumor, probably by killing tumor cells thanks to a peak of high drug concentration during their ...efficient tumor therapy and opens an avenue for ...

42

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en fr Signaling of integrin aE(CD103)ß7 and its role in functional activities of anti-tumor cytotoxic T lymphocytes Étude de la signalisation de l'intégrine αE(CD103)β7 dans les lymphocytes T cytotoxiques anti-tumoraux

... d'Ac anti-CD3 à faible dose a été utilisée pour visualiser une augmentation du Ca 2+ ...d'Ac anti-CD3 utilisée étant très faible, l'engagement simultané de CD103 est nécessaire pour obtenir une augmentation ...

229

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en fr Immuno-modulatory effects of neuropilin-1 on anti-tumor CD8 T cell functions Rôle de la Neuropiline-1 dans les fonctions effectrices des lymphocytes T CD8 antitumoraux

... DISCUSSION ET PERSPECTIVES I. Expression et régulation de la Nrp-1 et des iRs Nous avons mis en évidence que les TILs CD8 + peuvent exprimer la Nrp-1 à leur surface, que ce soit dans le modèle tumoral murin de mélanome ...

161

Demographic and clinical parameters influencing the short-term outcome of anti-tumor necrosis factor (infliximab) treatment in Crohn's disease

Demographic and clinical parameters influencing the short-term outcome of anti-tumor necrosis factor (infliximab) treatment in Crohn's disease

... Previous abdominal surgery 51 (37.2) 31 (30.1) 82 (34.2) CDAI = Crohn's Disease Activity Index; NSAID = nonsteroidal anti-inflammatory drugs. Statistical Analysis Data were analyzed by means of a stepwise logistic ...

8

Maintenance of cytomegalovirus-specific CD4pos T-cell response in rheumatoid arthritis patients receiving anti-tumor necrosis factor treatments.

Maintenance of cytomegalovirus-specific CD4pos T-cell response in rheumatoid arthritis patients receiving anti-tumor necrosis factor treatments.

... the anti-CMV CD4 pos T-cell response is enriched in the CD28 neg compartment [17,26], we measured the percentage of IFN-γ pos CD4 pos T cells within the CD28 neg compartment after exposure to CMV ...

9

Characterization of the anti-tumor activity of Inula viscosa, Retama monosperma, Marrubium vulgare and Ormenis eriolepis extracts from North Africa: Morocco

Characterization of the anti-tumor activity of Inula viscosa, Retama monosperma, Marrubium vulgare and Ormenis eriolepis extracts from North Africa: Morocco

... Liste d’abréviations BAD: Bcl-2-associated death promoter BAX: Bcl-2-associated X protein Bcl-xl: B-cell lymphoma-extra large Bcl-2: B-cell lymphoma 2 BIM: Bcl-2-like protein 11 B-NHL: B[r] ...

227

A small-molecule P2RX7 activator promotes anti-tumor immune responses and sensitizes lung tumor to immunotherapy

A small-molecule P2RX7 activator promotes anti-tumor immune responses and sensitizes lung tumor to immunotherapy

... 5 tumor cells were injected ...when tumor reached ~10–15 mm 2 , for a maximum of 20 days and mice received vehicle or HEI3090 (3 mg/kg in PBS, 10% DMSO) ...LLC tumor cell inoculation in WT mice and ...

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Latest Advances in Targeting the Tumor Microenvironment for Tumor Suppression

Latest Advances in Targeting the Tumor Microenvironment for Tumor Suppression

... well-established tumor-homing ...the tumor microenvironment [ 190 ...showed anti-tumor effects following injection of the genetically engineered MSCs to tumor-bearing ...promote ...

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