and B cell immune responses
CD4+ T cell-dependent and CD4+ T cell-independent cytokine-chemokine network changes in the immune responses of HIV-infected individuals
... NK cell receptors, including how HLA and KIR genetics affect the susceptibility of NK cells to HIV infection as well as disease progression (18, 19, ...TLR responses of NK ...increased ...
29
Armc5 deletion causes developmental defects and compromises T-cell immune responses
... function and mechanisms of action, except that gene mutations are associated with risks of primary macronodular adrenal gland ...hybridization, and generate Armc5 knockout mice, which are small in body ...
16
Effects of proton versus photon irradiation on (lymph) angiogenic, inflammatory, proliferative and anti-tumor immune responses in head and neck squamous cell carcinoma
... 1,2,4 and G Pagès 1,2 The proximity of organs at risk makes the treatment of head and neck squamous cell carcinoma (HNSCC) challenging by standard ...proliferation and mRNA levels for genes ...
14
P11-05. Induction of CD8+ T cell mediated immune responses through skin and mucosa: identification of immunostimulatory versus tolerogenic dendritic cells
... CTL responses was induced by newly recruited DC rather than skin/mucosal resident ...CCL20 and CCR6, and directly cross- present the Ag to CD8+ T ...mice and the con- tact sensitizer DNFB ...
2
P19-26. Directing macaque immune responses with an anti-dendritic cell HIV Gag p24 fusion protein vaccine
... Anti-Langerin and anti-DCIR mAb-based vaccines elicited comparable p24 specific T cell responses, whereas the anti-LOX-1-based vaccine induced relatively poor T cell ...antibody ...
2
The Immune Microenvironment in Clear Cell Renal Cell Carcinoma : The heterogeneous immune contextures accompanying CD8+ T cell infiltration in clear cell Renal Cell Carcinoma
... infections and cancer; in these contexts, PD-1+ cells often exhibit alterations in the production of several cytokines ...IFN-γ and TNF-α) and defective proliferative capacities (39), a phenomenon ...
117
Phenotyping of Adaptive Immune Responses in Inflammatory Diseases
... T cell clonality and/or TCR af finity measurements ( 13 , 14 , 16 ) ( Figures 1A, C ...proteins and overall T cell reactivity in patients ( 17 – 19 ) as well as clonality and af finity ...
9
CD8 T cell differentiation during immune responses
... Choriomeningitis Virus Infection 䌤 Ivana Munitic, 1 †* He ´le `ne Decaluwe, 2 † Ce ´sar Evaristo, 1 Sara Lemos, 1 Myriam Wlodarczyk, 3 Andrew Worth, 5 Agne `s Le Bon, 1 § Liisa K. Selin, 3 Yves Rivie `re, 4 James P. Di ...
212
Commensal-specific immune responses at the intestinal mucosa
... somatic cell nuclear transfer (SCNT) that carries a monoclonal TCR (Vα2 Vβ6) isolated from pTreg cells sorted from ...instrument and used as donors of nuclei for ...color and confirmed by PCR for ...
219
Host innate immune responses to Acinetobacter baumannii infection
... resistant) and complement- sensitive (serum sensitive) strains ( Garcia et ...) and found that the majority of the ...deposition and the alternative complement pathway was likely to be responsible ...
17
Epigenetic regulation of innate immune responses to infection
... Discussion and Perspectives ...innate immune cells is their ability to rapidly respond to intracellular and extracellular ...innate immune cells in response to an infectious agent (Bierne et ...
169
Bacterial flagellins: mediators of pathogenicity and host immune responses in mucosa.
... plants and mammals Similarly to mammals, plants detect MAMPs from pathogenic microorganisms, called general elicitors, via PRRs and then elicit a defence ...fungal cell wall constituents (e.g. ...
28
Phosphatase PTPN22 Regulates Dendritic Cell Homeostasis and cDC2 Dependent T Cell Responses
... regulates immune receptor activation. It functions by dephosphorylating Src and Syk family kinases operating proximal to immune-receptors such as TCR, BCR, and LFA-1 ( 32 – 36 ...cells ...
13
Intestinal epithelial cells instruct myeloid cell-mediated T-cell responses
... of B- and T-lymphocytes as well as macrophages (Mf), dendritic cells (DC), eosinophils and mast ...these immune cells were present in other tissues at such concentrations, they would be ...
85
Lysophosphatidylcholine is a natural adjuvant that initiates cellular immune responses.
... transport and distribute non polar lipids throughout the organism acquire additional function during the ...lysophospholipid and to stimulate the generation of mature DC from differentiating monocytes in ...
33
MicroRNA-29b Modulates Innate and Antigen-Specific Immune Responses in Mouse Models of Autoimmunity
... inflammation, immune- and metabolic pathways ...miRNAs and proteins from their cell of origin towards recipient cells ...mediated immune- stimulation exacerbating neurodegeneration ...
13
Bispecific, T-Cell-Recruiting Antibodies in B-Cell Malignancies.
... blinatumomab and the anti-PD-1 antibody Pembrolizumab enhanced T-cell function and induced an anti-leukemic response in a 12-year-old patient with refractory ALL ( 140 ...resistance and even ...
20
Biochemical Underpinnings of Immune Cell Metabolic Phenotypes
... a cell to oxidize fuels is intimately linked to its ability to perform effector functions and ...T cell subsets is associated with low levels of glucose transporters, while productive ...
25
Regulation of mucosal immune responses by anthrax edema toxin derivatives.
... membranes and secretions by mast cells and cause their degranulation with local histamine release [19] ...SIgA responses. The IgA-secreting B cells are primarily generated through the aid ...
145
Pathogen-Specific T Cell Polyfunctionality Is a Correlate of T Cell Efficacy and Immune Protection
... T cell responses against Leishmania major A second experimental dataset was composed of polyfunctionality profiles of Leishmania major-specific CD4 + T cells from the spleen of mice vaccinated against ...
19