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AMP-Activated Protein Kinases/metabolism

AMP-activated protein kinase as a target for pathogens: friends or foes?

AMP-activated protein kinase as a target for pathogens: friends or foes?

... Especially protein kinases are important regulators of virus-host interaction and many different host cell signaling pathways are subverted to enable the generation of the next round of infectious ...

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Beyond energy homeostasis: the expanding role of AMP-activated protein kinase in regulating metabolism

Beyond energy homeostasis: the expanding role of AMP-activated protein kinase in regulating metabolism

... AMPK-related kinases in the regulation of metabolism LKB1 is a master kinase that phosphorylates and activates AMPK and also a family of 12 closely related protein kinases, including SIK ...

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Octacalcium phosphate crystals directly stimulate expression
of inducible nitric oxide synthase through p38 and JNK
mitogen-activated protein kinases in articular chondrocytes

Octacalcium phosphate crystals directly stimulate expression of inducible nitric oxide synthase through p38 and JNK mitogen-activated protein kinases in articular chondrocytes

... involved. NO production was partially inhibited by low p38 inhibitor concentration whereas iNOS mRNA expression was markedly decreased, reflecting differences between iNOS protein production and activity and ...

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Place de l'AMP-activated protein kinase dans le preconditionnement ischemique renal.

Place de l'AMP-activated protein kinase dans le preconditionnement ischemique renal.

... ß 2013 Association Socie´te´ de ne´phrologie. Publie´ par Elsevier Masson SAS. Tous droits re´serve´s. A B S T R A C T Kidney transplantation represents the best treatment of end-stage renal disease. In addition to the ...

8

Are the IKKs and IKK-related kinases TBK1 and IKK-ε similarly activated ?

Are the IKKs and IKK-related kinases TBK1 and IKK-ε similarly activated ?

... the protein NEMO [10] ...scaffold protein required for the assembly of this kinase complex in these pathways [12,13,25] ...inhibitory protein p100 through an IKK-a-dependent pathway [29–31] ...

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Octacalcium phosphate crystals directly stimulate expression of inducible nitric oxide synthase through p38 and JNK mitogen-activated protein kinases in articular chondrocytes.

Octacalcium phosphate crystals directly stimulate expression of inducible nitric oxide synthase through p38 and JNK mitogen-activated protein kinases in articular chondrocytes.

... pharmacological and cytokine inhibitors, we observed that OCP crystals induced NO production and inducible NOS mRNA activation were regulated at both the transcriptional and the translational levels; were independent ...

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AMP-activated protein kinase is dispensable for maintaining ATP levels and for survival following inhibition of glycolysis, but promotes tumour engraftment of ras-transformed fibroblasts

AMP-activated protein kinase is dispensable for maintaining ATP levels and for survival following inhibition of glycolysis, but promotes tumour engraftment of ras-transformed fibroblasts

... the AMP- activated protein kinase (AMPK) [2, 16, 27, ...serine/threonine protein kinase involved in the control of energy homeostasis ...heterotrimeric protein comprising a catalytic α ...

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en fr AMP-activated protein kinase : Screening for novel membrane substrates and creatine kinase phosphorylation linked to specific subcellular compartment La protéine kinase activée par AMP : Criblage de nouveaux substrats membranaires et phosphorylation de la créatine kinase liée à une compartimentation subcellulaire

... de la procédure et la pureté des protéines. Dans ce travail de thèse, un système de chromatographie thermostaté haut de gamme (Äkta Explorer) a été modifié de telle manière qu'une purification automatique des protéines ...

132

The release of pro-inflammatory cytokines is mediated via mitogen-activated protein kinases rather than by the inflammasome signalling pathway in keratinocytes

The release of pro-inflammatory cytokines is mediated via mitogen-activated protein kinases rather than by the inflammasome signalling pathway in keratinocytes

... MSU treatment significantly increased the abundance of IL-1β, IL-6 and IL-8/CXCL8 mRNA in both HEK and HaCaT cells (Figure 1). Up-regulation of the pro-IL-1β gene suggests that keratinocytes may produce activated ...

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Rôles physiologiques de l’AMP-activated protein kinase (AMPK)

Rôles physiologiques de l’AMP-activated protein kinase (AMPK)

... L’AMP-activated protein kinase (AMPK), enzyme ubiquitaire, est proposée comme le détecteur métabolique de la cellule lui per- mettant de s’adapter aux modifications de son environnement [1] ...

2

Recent Advances in Pain Management: Relevant Protein Kinases and Their Inhibitors

Recent Advances in Pain Management: Relevant Protein Kinases and Their Inhibitors

... Keywords: protein kinases; inhibitors; pain ...symptoms. Protein kinases are transferases that catalyze the transfer of a phosphate group from ATP to a hydroxy group of serine/threonine or ...

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AMP-Activated Protein Kinase Signalling

AMP-Activated Protein Kinase Signalling

... Int. J. Mol. Sci. 2019, 20, 766 2 of 5 As reviewed by Janzen et al., in skeletal muscle, AMPK activity is regulated by glycogen content [ 3 ]. Glycogen physically binds AMPK, modifying its conformation to inhibit its ...

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The Adaptor Protein p66Shc Inhibits mTOR-Dependent Anabolic Metabolism

The Adaptor Protein p66Shc Inhibits mTOR-Dependent Anabolic Metabolism

... glucose metabolism through the pentose phosphate and hexosamine biosynthesis pathways In addition to the role of these molecules in glycolysis, G6P and F6P are precursors of the hexosamine biosynthesis and the ...

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Lectin receptor kinases participate in protein-protein interactions to mediate plasma membrane-cell wall adhesions in Arabidopsis.

Lectin receptor kinases participate in protein-protein interactions to mediate plasma membrane-cell wall adhesions in Arabidopsis.

... IPI-O protein without the putative signal sequence, was cloned into the pMALc vector in fusion with MBP (maltose binding protein) (Senchou et ...fusion protein as well as recombinant mutated proteins ...

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Mitogen-activated protein kinase-activated protein kinase 2 mediates resistance to Hydrogen peroxide-induced oxidative stress in Human hepatobiliary Cancer cells

Mitogen-activated protein kinase-activated protein kinase 2 mediates resistance to Hydrogen peroxide-induced oxidative stress in Human hepatobiliary Cancer cells

... Figure 7 – Regulation of MK2 pathway by the scaffold protein EBP50. (A) MK2 protein owns a typical PDZ motif at its COOH-tail, LTRL. (B-C) MK2 interacts with EBP50. GST pull-down analysis was performed by ...

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Citrulline modulates muscle protein metabolism in old malnourished rats

Citrulline modulates muscle protein metabolism in old malnourished rats

... tein metabolism in old malnourished rats. Am J Physiol Endocrinol Metab 291: E582–E586, 2006. First published April 11, 2006; doi:10.1152/ajpendo.00398.2005.—Protein energy malnutrition is common in the ...

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L’AMP-activated protein kinase hypothalamique, régulateur essentiel du poids et de la prise alimentaire

L’AMP-activated protein kinase hypothalamique, régulateur essentiel du poids et de la prise alimentaire

... L’AMP-activated protein kinase (AMPK), constituée de trois sous-unités (une sous-unité catalytique α 1 ou α 2, deux sous-unités régulatrices β et γ ), est une enzyme ubiquitaire dont l’acti- vité dépend de ...

2

Recent Advances in Pain Management: Relevant Protein Kinases and Their Inhibitors

Recent Advances in Pain Management: Relevant Protein Kinases and Their Inhibitors

... Keywords: protein kinases; inhibitors; pain ...symptoms. Protein kinases are transferases that catalyze the transfer of a phosphate group from ATP to a hydroxy group of serine/threonine or ...

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