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all-trans retinoic acid

All-trans retinoic acid induces oxidative phosphorylation and mitochondria biogenesis in adipocytes

All-trans retinoic acid induces oxidative phosphorylation and mitochondria biogenesis in adipocytes

... of all- trans retinoic acid (ATRA) on white adipose tissue (WAT) oxidative and thermogenic ca- pacity has been described and linked to an in vivo fat-lowering effect of ATRA in ...

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Efficiency of All-Trans Retinoic Acid on Gastric Cancer: A Narrative Literature Review

Efficiency of All-Trans Retinoic Acid on Gastric Cancer: A Narrative Literature Review

... into retinoic acids. All-trans retinoic acid (ATRA), which has pro-differentiating properties, has revolutionized the prognosis of acute promyelotic leukemia by increasing its remission ...

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All-trans-retinoic acid represses chemokine expression in adipocytes and adipose tissue by inhibiting 1 NF-κB signaling 2 3

All-trans-retinoic acid represses chemokine expression in adipocytes and adipose tissue by inhibiting 1 NF-κB signaling 2 3

... [10] Bonet ML, Canas JA, Ribot J, Palou A. Carotenoids and their conversion products in the control of adipocyte function, adiposity and obesity. Arch Biochem Biophys. 2015;572:112-25. [11] Tourniaire F, Gouranton E, von ...

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Isocitrate dehydrogenase 1 mutations prime the all-trans retinoic acid myeloid differentiation pathway in acute myeloid leukemia

Isocitrate dehydrogenase 1 mutations prime the all-trans retinoic acid myeloid differentiation pathway in acute myeloid leukemia

... MAT ERI ALS AND MET HODS AML patient samples. AML and normal bone marrow samples were obtained from patients at the Department of Hematol‑ ogy (Centre Hospitalier Universitaire de Toulouse [CHU], Toulouse, France) after ...

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Complex context relationships between DNA methylation and accessibility, histone marks, and hTERT gene expression in acute promyelocytic leukemia cells: perspectives for all‐ trans retinoic acid in cancer therapy

Complex context relationships between DNA methylation and accessibility, histone marks, and hTERT gene expression in acute promyelocytic leukemia cells: perspectives for all‐ trans retinoic acid in cancer therapy

... remission, all APL patients present a decreased DNA methylation in the distal domain of the hTERT core promoter, as compared to patient at diagnosis, leading to a pattern of methylation similar to that in healthy ...

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Two functionally redundant sources of retinoic acid secure spermatogonia differentiation in the seminiferous epithelium

Two functionally redundant sources of retinoic acid secure spermatogonia differentiation in the seminiferous epithelium

... mammals, all-trans retinoic acid (ATRA) is instrumental to ...lacking all RALDH activities in the seminiferous epithelium ...against all expectations, the GC-derived source does ...

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Retinoic Acid Engineered Amniotic Membrane Used as Graft or Homogenate: Positive Effects on Corneal Alkali Burns

Retinoic Acid Engineered Amniotic Membrane Used as Graft or Homogenate: Positive Effects on Corneal Alkali Burns

... with all-trans retinoic acid (atRA); the other groups were treated with eye drops six times daily, and these comprised homogenates of AM that were untreated or pretreated with ...Table). ...

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Retinoic acid synthesis by ALDH1A proteins is dispensable for meiosis initiation in the mouse fetal ovary

Retinoic acid synthesis by ALDH1A proteins is dispensable for meiosis initiation in the mouse fetal ovary

... environment. All-trans retinoic acid (ATRA) signaling is considered the key pathway that promotes Stra8 (stimulated by retinoic acid 8) expression and, in turn, meiosis ...

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PLZF is a negative regulator of retinoic acid receptor transcriptional activity.

PLZF is a negative regulator of retinoic acid receptor transcriptional activity.

... The exact biological role of PLZF remains to be estab- lished. However, its localization to nuclear bodies [11], which are nuclear structures associated to a central, tran- scriptional regulatory role [12], as well as ...

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Retinoic acid receptors interfere with the TGF-beta/Smad signaling pathway in a ligand-specific manner.

Retinoic acid receptors interfere with the TGF-beta/Smad signaling pathway in a ligand-specific manner.

... 37°C in a 5% CO 2 - 95% air atmosphere. In some experiments, charcoal-stripped FCS was used to alleviate the potential influence of FCS-contained lipids (e.g. retinoids). No difference in the outcome of the experiments ...

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An Unexpected Mode Of Binding Defines BMS948 as A Full Retinoic Acid Receptor β (RARβ, NR1B2) Selective Agonist

An Unexpected Mode Of Binding Defines BMS948 as A Full Retinoic Acid Receptor β (RARβ, NR1B2) Selective Agonist

... Introduction Retinoic acids and their analogs, referred to as retinoids, exert their pleiotropic effects through three retinoic acid receptor subtypes [RAR α (NR1B1), RARβ (NR1B2) and RARγ (NR1B3)] ...

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Retinoic acid protects human breast cancer cells against etoposide-induced apoptosis by NF-kappaB-dependent but cIAP2-independent mechanisms.

Retinoic acid protects human breast cancer cells against etoposide-induced apoptosis by NF-kappaB-dependent but cIAP2-independent mechanisms.

... three retinoic acid receptors (RARa, -b, and -g) and three reti- noid-X-receptors (RXRa, -b, and -g) which form RAR/ RXR heterodimers that are believed to correspond to the in vivo mediators of the ...

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Retinoic acid improves nephrotoxic serum–induced glomerulonephritis through activation of podocyte retinoic acid receptor α

Retinoic acid improves nephrotoxic serum–induced glomerulonephritis through activation of podocyte retinoic acid receptor α

... the retinoic acid receptors (RAR) and the retinoid X receptors (RXR), which have distinct cellular functions and are expressed in a variety of tissues including the kidney 12 ...While all- ...

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Lysyl oxidase-like 4 involvement in retinoic acid epithelial wound healing

Lysyl oxidase-like 4 involvement in retinoic acid epithelial wound healing

... Aurélie Comptour 1 , Marion Rouzaire 1 , Corinne Belville 1,2 , Nicolas Bonnin 1,3 , Estelle Daniel 1,3 , Frédéric Chiambaretta 1,3 , Loïc Blanchon 1 & Vincent Sapin 1 Vitamin A and its active forms (retinoic ...

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Retinoic acid regulates olfactory progenitor cell fate and differentiation.

Retinoic acid regulates olfactory progenitor cell fate and differentiation.

... 2 Retinoic acid signaling affects olfactory neural ...whereas all-trans-RA (AT-RA) treatment leads to a basal location of Pax6+ cells ...

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Retinoic acid receptor α as a novel contributor to adrenal cortex structure and function through interactions with Wnt and Vegfa signalling

Retinoic acid receptor α as a novel contributor to adrenal cortex structure and function through interactions with Wnt and Vegfa signalling

... Primary aldosteronism (PA) is the most frequent form of secondary arterial hypertension. Mutations in different genes increase aldosterone production in PA, but additional mechanisms may contribute to increased cell ...

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Crosstalk between retinoic acid and sex-related genes controls germ cell fate and gametogenesis in Medaka

Crosstalk between retinoic acid and sex-related genes controls germ cell fate and gametogenesis in Medaka

... Sex determination (SD) is a highly diverse and complex mechanism. In vertebrates, one of the first morphological differences between the sexes is the timing of initiation of the first meiosis, where its initiation occurs ...

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Contribution of trans -aconitic acid to DPPH scavenging ability in different media

Contribution of trans -aconitic acid to DPPH scavenging ability in different media

... c ontaining 20 µM of vitamin C had a synergy effect Beyond this c oncentration, TM showed an additive effe c t. Antioxidants are listed as additives in food ( Perrin & Meyer, 2002; Shahidi, 2000 1 cosmetic ( Alander, ...

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Collecting duct cells show differential retinoic acid responses to acute versus chronic kidney injury stimuli

Collecting duct cells show differential retinoic acid responses to acute versus chronic kidney injury stimuli

... LacZ mice, Adriamycin-induced heavy albuminuria was associated with reduced RA/RAR activity in CD cells. In cultured CD cells, RA/RAR activity was repressed by acetylcholine, albumin, aldosterone, angiotensin II, high ...

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Savoirs Trans

Savoirs Trans

... l’inventivité des parcours individuels, les trans furent réduits à n’être qu’une quantité tour à tour pathologique ,subversive ou transgressive. Et, n’en déplaise aux médias, les déclarations de Roselyne Bachelot ...

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