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adenosine receptor

Adenosine Receptor Antagonists Including Caffeine Alter Fetal Brain Development in Mice

Adenosine Receptor Antagonists Including Caffeine Alter Fetal Brain Development in Mice

... INTRODUCTION Neural development is strongly influenced by external (for example, environmental) factors including certain drugs ( 1). These drugs are known to modify cell migration ( 2, 3) and synapse formation (4, 5), ...

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Cardiac myocyte–secreted cAMP exerts paracrine action via adenosine receptor activation

Cardiac myocyte–secreted cAMP exerts paracrine action via adenosine receptor activation

... distinct adenosine recep- tor profiles of cardiac cells affect their response to exogenously added ...Since adenosine receptors couple to G s that regu- late the activity of adenylyl cyclase, quantitation ...

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en
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en fr Neurogenetics of the Human Adenosine Receptor Genes: Genetic Structures and Involvement in Brain Diseases Neurogénétique des gènes humains des récepteurs de l'adénosine: structures génétiques et implication dans les maladies cérébrales

... Abstract Adenosine receptors are G-protein-coupled receptors involved in a wide range of physiological and pathological phenomena in most mammalian ...the adenosine receptors (encoded by the ADORA1, ...

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Adenosine Receptor Profiling Reveals an Association between the Presence of Spare Receptors and Cardiovascular Disorders

Adenosine Receptor Profiling Reveals an Association between the Presence of Spare Receptors and Cardiovascular Disorders

... Abstract: Adenosine and its receptors exert a potent control on the cardiovascular ...spare adenosine receptors appear to compensate for a low extracellular adenosine level and/or a low ...

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Adenosine receptor signaling: a key to opening the blood–brain door

Adenosine receptor signaling: a key to opening the blood–brain door

... that adenosine receptor (AR) activation can modulate blood–brain bar‑ rier (BBB) permeability and the implications for disease states and drug ...nucleoside adenosine is a potent modulator of a large ...

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RhoA inhibition is a key step in pituicyte stellation induced by A(1)-type adenosine receptor activation.

RhoA inhibition is a key step in pituicyte stellation induced by A(1)-type adenosine receptor activation.

... in Adenosine-induced Pituicyte Stellation As it has previously been shown that astrocyte stellation is controlled by a member of the Rho family of proteins (Ramakers and Moolenaar, 1998), which are small GTPases ...

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The NLRP3 inflammasome is activated by nanoparticles through ATP, ADP and adenosine.

The NLRP3 inflammasome is activated by nanoparticles through ATP, ADP and adenosine.

... active adenosine triphosphate (ATP) release and subsequent ATP, adenosine diphosphate (ADP) and adenosine receptor signalling are required for inflammasome ...B receptor expression, ...

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Ticagrelor Increases Adenosine Plasma Concentration in Patients With an Acute Coronary Syndrome

Ticagrelor Increases Adenosine Plasma Concentration in Patients With an Acute Coronary Syndrome

... on adenosine receptor A 1 or A2 A and did not affect ...inhibited adenosine uptake by RBC, leading to the increase in APC similar to what was observed for dipyridamole (19,20) ...

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CD39/Adenosine Pathway Is Involved in AIDS Progression.

CD39/Adenosine Pathway Is Involved in AIDS Progression.

... that adenosine plays an important non-redundant role in the regulation of T cell activation ...the adenosine receptor agonist CGS21680 [18], we confirmed the involvement of CD39/ adenosine ...

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de en Adenosinhypersensitivität und atrioventrikulärer Block Adenosine hypersensitivity and atrioventricular block

... block Adenosine, sometimes called the “retalia- torymetabolite”, is a ubiquitous substance that is released under several physiolog- ical and pathological conditions ...of adenosine on different structures ...

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Adenosine receptors control HIV-1 Tat-induced inflammatory responses through protein phosphatase

Adenosine receptors control HIV-1 Tat-induced inflammatory responses through protein phosphatase

... CGS 21680 increases cytosolic serine/threonine phosphatase activity Because okadaic acid, a serine/threonine phosphatase inhibitor, reversed the anti-TNF-a effects of CGS 21680, we hypothesized that adenosine ...

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Blockade of Adenosine A2A receptors prevents staurosporine-induced apoptosis of rat hippocampal neurons

Blockade of Adenosine A2A receptors prevents staurosporine-induced apoptosis of rat hippocampal neurons

... Goswami, R., Dawson, S. A., Dawson, G., 1998. Cyclic AMP protects against staurosporine and wortmannin-induced apoptosis and opioid-enhanced apoptosis in both embryonic and immortalized (F-1lk7) neurons. J. Neurochem. ...

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LIGAND-RECEPTOR INTERACTIONS

LIGAND-RECEPTOR INTERACTIONS

... These difficulties were addressed in a later study (Pierres et al., 1998d) made on the homotypic interaction between spheres and surfaces coated with binding sites of cadherins, which are important cell adhesion ...

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Adsorption of nucleotides on biomimetic apatite: the case of adenosine 5′ monophosphate (AMP)

Adsorption of nucleotides on biomimetic apatite: the case of adenosine 5′ monophosphate (AMP)

... This work investigates the interaction between the nucleotide adenosine 5 ′ monophosphate molecule (AMP) and a biomimetic nanocrystalline carbonated apatite as a model for bone mineral. The analogy of the apatite ...

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2′-O Methylation of Internal Adenosine by Flavivirus NS[subscript 5] Methyltransferase

2′-O Methylation of Internal Adenosine by Flavivirus NS[subscript 5] Methyltransferase

... RNA substrates Two types of RNA substrates were prepared for methylation analysis. Type one RNA contains non–viral sequence. Synthetic RNA oligos include (A) 12 , (Am) 12 (‘‘m’’ indicates 29-O-methyl Figure 7. Effects of ...

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Adsorption of nucleotides on biomimetic apatite: the case of adenosine 5′ monophosphate (AMP)

Adsorption of nucleotides on biomimetic apatite: the case of adenosine 5′ monophosphate (AMP)

... protein kinase (AMPK) is an enzyme that plays a role in cellu- lar energy homeostasis. In the presence of AMP, the activity of AMPK is increased so that AMPK is regulated by AMP [30] . The effects of AMP are two-fold: a ...

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Cardioprotective effects of adenosine within the border and remote areas of myocardial infarction.

Cardioprotective effects of adenosine within the border and remote areas of myocardial infarction.

... In our study, CADO was unable to significantly pro- tect the heart from the development of adverse LV re- modelling, as assessed by LV volumes and EF. These results differ from those of Wakeno and colleagues [8], where a ...

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Vasopressin and oxytocin reverse adenosine-induced pituicyte stellation via calcium-dependent activation of Cdc42.

Vasopressin and oxytocin reverse adenosine-induced pituicyte stellation via calcium-dependent activation of Cdc42.

... i ) was measured with the ratiometric, membrane-permeable, fluorescent probe Fura-2 AM. Briefly, pituicyte cultures were incubated for 45 min at 37 °C in the presence of 5 µM Fura-2 AM + 0.01% pluronic acid (+ 10 µM ...

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Sumoylation of the Progesterone Receptor and of the Steroid Receptor Coactivator SRC-1

Sumoylation of the Progesterone Receptor and of the Steroid Receptor Coactivator SRC-1

... nuclear receptor-interacting region 1 ...nuclear receptor binding LXXLL motifs is known to be modu- lated by adjacent amino acids (58), we examined the effect of sumoylation on PR-SRC-1 ...of ...

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The orphan nuclear receptor, liver receptor homolog-1 (LRH-1, NR5A2) regulates decidualization

The orphan nuclear receptor, liver receptor homolog-1 (LRH-1, NR5A2) regulates decidualization

... 2 receptor (BMPR2) in the mouse uterus leads to female infertility, primarily due to a defect in stromal decidualization, caused by the disregulation of the Cyclin D3 (Ccnd3), a key mediator of G 2 phase arrest in ...

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