active pharmaceutical ingredients
Dissolution enhancement of active pharmaceutical ingredients in Eudragit E100 by melt extrusion coupled with supercritical carbon dioxide
... crystalline active pharmaceutical ingredients (APIs) in polymers for dissolution enhancement, which is achieved by destructing their crystal ...some active compounds can be an obstacle to its ...
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Transfer of active pharmaceutical ingredients (API) Raman library from bench top towards handheld spectrometers
... of active pharmaceutical ingredients (API) on a lab spectrometer and to show that a transfer to different Raman systems using the Hit Quality Index (HQI) algorithm is ...
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Composite Hydrogels Laden with Crystalline Active Pharmaceutical Ingredients of Controlled Size and Loading
... (d) Disso- lution profile of dried composite hydrogels with different crystal sizes prepared by controlling the droplet size at fixed API concen- tration (C sat =C satFEN ). The inset sh[r] ...
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Design of a rapid, continuous, small-scale device for creating dry powders from concentrated suspensions containing active pharmaceutical ingredients
... The final design is a two-stage design made up of a drum dryer, utilizing the flaking method, and a tubular screw dryer utilizing the vacuum method.. The function and de[r] ...
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A new combined LC (ESI+) MS/MS QTOF impurity fingerprinting and chemometrics approach for discriminating active pharmaceutical ingredient origins: example of simvastatin
... of active pharmaceutical ingredients (API) and finished ...the pharmaceutical industry converge on greater and more systematic ...of pharmaceutical manufacturing to new emerging markets ...
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Comparative Study of Two Processes to Improve the Bioavailability of an Active Pharmaceutical Ingredient: Kneading and Supercritical Technology
... in pharmaceutical formu- lations is the bioavailability of the active ...new Active Pharmaceutical Ingredients (API) are very poorly water ...low-solubility active molecules with ...
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Lipids and polymers in pharmaceutical technology: lifelong companions
... 6. Conclusions Despite centuries of use in human health history, lipids and poly- mers have not yet unraveled their full potential as pharmaceutical ex- cipients. Both exhibit great versatility in terms of ...
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Recent developments of marine ingredients for food and nutraceutical applications: a review.
... and active ingredients is the ‘big dream’ of marine biotechnology industry: these products are low in volume but with high value, and there is a tremendous potential for these innovative molecules ...
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Continuous Plug Flow Crystallization of Pharmaceutical Compounds
... supersaturation in a plug flow reactor with a T mixer. 4 The weight mean size of benzoic acid decreased from 9.3 μm to 3.5 μm with increasing initial supersaturation ratio from 3.5 to 5.5. Rivera and Randolph found that ...
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Chitosan: a versatile platform for pharmaceutical applications
... applications, PEGs with molecular weights of 2,000 to 10,000 Da are typically used to ensure renal clearance of degradation products. It is also possible to use bifunctional, α,ω-diami[r] ...
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Bayesian Design Space applied to Pharmaceutical Development
... the pharmaceutical industry, the International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH), that regroups experts from the pharmaceutical ...
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Demand and Supply Stability in the Pharmaceutical Industry
... Summary: A pharmaceutical company is facing instability in the planning process. Using analysis of real data, Root Cause Analysis, and interviews in the field, the thesis aims to investigate the main causes that ...
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Continuous blending of dry pharmaceutical powders
... 5. Flavors, Colors and Sweeteners are added in small quantities to enhance the look, feel and taste of the tablet or capsule and usually do not serve any other purpose. Domike [25] and Ngai [71] have studied the ...
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Applying System Engineering to Pharmaceutical Safety
... A final potential limitation of the FDAAA legislation is that it requires gradual reduction of permitted conflict of interest waivers for advisory committee members. This requirement responds, in part, to criticisms in ...
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View of Carbon monoxide: a new pharmaceutical agent?
... Introduction Small amounts of carbon monoxide (CO) are continuously produced in mammals. The intracellular levels of this gas- eous molecule can markedly increase under stressful condi- tions following induction of heme ...
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Who cites non-English-language pharmaceutical articles?
... of pharmaceutical international journals; we selected journals on a practical considerations basis (availability in our University ...of pharmaceutical colleges in universities of some countries ...
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Application of EU Competition Law in the Pharmaceutical Sector
... the Pharmaceutical Sector Inquiry, which is somewhat ironic given that, in this Report, the Commission explicitly disavowed reaching any conclusions concerning the application of competi- tion law in the ...
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Continuous processing of multiphase reactions for pharmaceutical applications
... Chapter 5 demonstrates a cost-effective and scalable electrochemical flow cell engineered for the N- hydroxyphthalimide (NHPI) mediated electrochemical aerobic oxidation[r] ...
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Computer-aided rational solvent selection for pharmaceutical crystallization
... Elucidating of the interactions between solvent and solute molecules, understanding the mechanism underlying the solvent effects on each aspect of the crystal properti[r] ...
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Pharmaceutical Applications of Molecular Tweezers, Clefts and Clips
... Abstract: Synthetic acyclic receptors, composed of two arms connected with a spacer enabling molecular recognition, have been intensively explored in host-guest chemistry in the past decades. They ...
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