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18 résultats avec le mot-clé: 'γδ t cells'

Diversity of Tumor-Infiltrating, γδ T-Cell Abundance in Solid Cancers

Similarly to normal tissues, γδ T-cell density was heterogeneous in the cancer types, with medium-to-high γδ T-cell density in breast, colon, and ovarian tumors, and few or no

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2021
Casting a wider net: Immunosurveillance by nonclassical MHC molecules

αβ T cells, alpha beta T cells; CD1, (involved in the presentation of lipid antigens to T cells); CDR, Complementarity-determining region; γδ T cells, gamma delta T cells; HLA,

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2021
γδ T cells amplify Blomia tropicalis -induced allergic airway disease

γδ T cells amplify Blomia tropicalis -induced allergic airway disease... gd T cells amplify Blomia tropicalis-induced allergic airway disease

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2021
Unexpectedly late expression of intracellular CD3ϵ and TCR γδ proteins during adult thymus development

Although it is formally possible that icTCR γδ1 DN4 thymocytes represent mature γδ T cells which have internalized the γδ TCR or ‘δ-selected’ αβ lineage-committed cells

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2021
Harnessing γδ T cells in anticancer immunotherapy

(e) Patients can be treated either by infusion of ex vivo expanded ɣδ T cells (as delineated in a–d) or by direct in vivo ɣδ T cell activation using

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2021
Ozone-Induced Aryl Hydrocarbon Receptor Activation Controls Lung Inflammation via Interleukin-22 Modulation

Lung cells recruitment (total cells, neutrophils, macrophages, ILC2, ILC3, αβ, and γδ T cells) (B), T H 2 cytokines (IL-4, IL-5) (C), AHR (D), and remodeling parameters

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2021
CD3(bright) signals on γδ T cells identify IL-17A-producing Vγ6Vδ1(+) T cells.

Gated pulmonary  T cell subsets were screened for IL-17A production based on their CCR6 expression. One representative experiment out of two is

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2021
The human fetal thymus generates invariant effector γδ T cells

In summary, fetal HSPC-derived γδ T cells (using the in vitro T cell development system OP9DL1) share with ex vivo fetal γδ thymoctyes: (i) a functional effector program; (ii) low

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2022
Synergistic targeting of breast cancer stem-like cells by human γδ T cells and CD8+ T cells

A similar γδ T-cell- induced upregulation of MHC class I and CD54 expression was seen with non-CSCs and parental HMLER cells, as well as with a panel of luminal-like and

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2021
Commensal Microbiota Promote Lung Cancer Development via γδ T Cells

Consistent with our data from the mouse model, we also demonstrated the association between local dysbiosis and human non-small cell lung cancer via PathSeq analysis, and we

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2021
Mechanisms of Bacterial Superinfection Post-influenza: A Role for Unconventional T Cells

Whilst the use of experimental models suggests a role for NKT cells and γδ T cells in bacterial superinfection post-influenza (the potential role of MAIT cells has not yet

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2021
Changes in the NK Cell Repertoire Related to Initiation of TB Treatment and Onset of Immune Reconstitution Inflammatory Syndrome in TB/HIV Co-infected Patients in Rio de Janeiro, Brazil—ANRS 12274

Natural killer (NK) cells, invariant NKT cells (iNKT), γδ T cell subsets, and in vitro NK functional activity were characterized by multiparametric flow cytometry in the

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2021
Émissions azotées au champ et performances des machines lors de l'épandage de boues issues du traitement des eaux usées

Tableau 17 : Coefficient d’équivalence engrais de l’azote des différents types de boues apportées pour chaque système de culture étudié ...33.. Tableau 18 :

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2021
Visualization of Some Energy Levels of Even-Even Nuclei

When departing from the closed shell (Near Magic) with the increase of the valence nucleon number N, the shape changes from spherical vibrator to deformed rotor, passing

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2021
Thymic development and peripheral functional polarisation of human Vγ9Vδ2 T cells

In sharp contrast, the other blood γδ T cell subsets (grouped as non- Vγ9Vδ2 T cells, not responding to phosphoantigens), while also showing TCR repertoire publicity at the

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2021
Subpopulations of bovine WC1+ γδ T cells rather than CD4+CD25highFoxp3+ T cells act as immune regulatory cells ex vivo

(c) Dotplots representing intracellular staining of IL-10 in bovine PBMC gated for live cells after Con A stimulation + Brefeldin A, surface stained with anti-bovine CD21, NKp46,

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2021
Insights into the physiology of the gamma-delta T Physiologie des lymphocytes T gamma-delta dans l'interaction du cytomégalovirus avec son hôte immunodéprimé

Proliferation and viability of Vδ2 neg γδ T cells at day 14, 21 and 28 of culture and of CMV-specific αβ T cells at day 9 and 16 of culture were performed. Representative donor for

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2021
prenatal Betamethasone interferes with immune system development and alters target cells in autoimmune diabetes

In vitro, betamethasone decreased lymphocyte viability and induced maturation- resistant dendritic cells, which in turn impaired γδ T cell proliferation and decreased IL-17

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2022

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