β1-integrin
The sVEGFR1-i13 splice variant regulates a β1 integrin/VEGFR autocrine loop involved in the progression and the response to anti-angiogenic therapies of squamous cell lung carcinoma
... encoding β1 integrin (β1) and treated (+) or not (−) with 10 µM KI8751 for 24 additional hours (left panels) or 10 µg/ml bevacizumab for 72 h (right ...VEGFR2, β1 integrin or ...
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en fr β1 integrin and its regulator ICAP-1α functions during osteogenesis : implication for osteoblast proliferation, differentiation and function L’intégrine β1 et de son régulateur ICAP-1α dans l’ostéogenèse : rôle dans la prolifération, la différenciation et la fonction ostéoblastiques
... Intégrine β1, ICAP-1α, YAP, BMP-2, Ostéoblaste, Matrice extracellulaire β1 integrin and its regulator ICAP-1α functions during osteogenesis : implication for osteoblast proliferation, differentiation ...
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Tetraspanin 8 is a novel regulator of ILK-driven β1 integrin adhesion and signaling in invasive melanoma cells.
... of β1-integrins, few focused on its involvement in integrin ...of β1-integrin clusters, leading to attenuated cell-matrix ...of β1- integrins with FAK-paxillin, especially as Tspan8 ...
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VEGF165b, a splice variant of VEGF-A, promotes lung tumor progression and escape from anti-angiogenic therapies through a β1 integrin/VEGFR autocrine loop
... cutaneous xenografts having received or not bevacizumab (7.5 mg/kg) once a week. Scale bar = 50 µm. (d) H358 or H1299 cells were treated, or not (NT), for 72 hours with either 5 µM cisplatin or a combination of 5 µM ...
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β1A integrin is a master regulator of invadosome organization and function.: β1 integrin control of invadosomes
... β1A integrin and the location of the main PKC ...pOBL-SrcYF β1 -/- cells. The non-phosphorylatable mutant of β1 at this site (S785A) has no effect on rosette ...on β1 is a major target of PKC ...
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Specificities of β1 integrin signaling in the control of cell adhesion and adhesive strength.
... domain of 1 that controls Rho activity. The role of individual Rho GTPases in fibronectin matrix remodelling has been examined by selectively down regulating their expression in cultured endothelial cells. No ...
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Osteoblast mineralization requires beta1 integrin/ICAP-1-dependent fibronectin deposition.
... with β1 integrin, is important for translocation of β1 integrins into fibrillar adhesions, which are required for proper fibronectin self assembly into ...
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Stromal integrin alpha11 regulates PDGFR-beta signaling and promotes breast cancer progression.
... (19), integrin α11+ cell subset is unlikely to be a pericyte subpopulation, as α11 integrin positivity poorly correlates with αSMA or ...between integrin α11 and FAP (22%) might reflect a partial ...
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alpha7B integrin changes in mdx mouse muscles after L-arginine administration.
... α7Β integrin localisation and function in muscle ...major integrin complex of cardiac and skeletal muscle (α7β1) is also concentrated in costameres ...anti-β1 integrin subunit co-precipited ...
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Endothelin-3 stimulates cell adhesion and cooperates with β1-integrins during enteric nervous system ontogenesis
... and β1-integrins are required for the colonization of the embryonic gut by enteric neural crest cells (ENCCs) to form the enteric nervous system ...(ENS). β1-integrin-null ENCCs exhibit migratory ...
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Dystrophin Dp71f associates with the beta1-integrin adhesion complex to modulate PC12 cell adhesion.
... the β1-integrin adhesion complex To confirm the interaction of Dp71f with β1integrin and the adhesion-associated proteins, lysates obtained from wild-type or antisense-Dp71 cells were immunoprecipitated ...
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β1D integrin splice variant stabilizes integrin dynamics and reduces integrin signaling by limiting paxillin recruitment
... β1A integrin is the specific expression of the β1D integrin isoform in cardiomyocytes and differentiated myotubes of skeletal muscle (Belkin et ...β1D integrin isoform in myoblasts or fibroblasts ...
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Integrin β1 Optimizes Diabetogenic T Cell Migration and Function in the Pancreas
... anti-β1 integrin mAb treatment affected both velocity and directionality of T cells indicates that lymphocytes do not only align along paths of least resistance in the PA, but that fibronectin fibers also ...
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αVβ3 integrin-targeted microSPECT/CT imaging of inflamed atherosclerotic plaques in mice
... Background: α V β 3 -integrin is expressed by activated endothelial cells and macrophages in atherosclerotic plaques and may represent a valuable marker of high-risk plaques. We evaluated 99m Tc-maraciclatide, an ...
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The Pseudomonas aeruginosa lectin LecB causes integrin internalization and inhibits epithelial wound healing
... e Department of Biology, University of Fribourg, Fribourg, Switzerland f Department of Dermatology, Medical Center, Albert Ludwigs University Freiburg, Freiburg, Germany g Univ. Grenoble Alpes, CNRS, CERMAV, Grenoble, ...
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Loss of Ena/VASP interferes with lamellipodium architecture, motility and integrin-dependent adhesion
... integrin-dependent adhesion is consistent with very recent work showing its specific requirement for FA maturation, cell-matrix adhesion and mechanosensing ( Puleo et ...
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Brag2 differentially regulates β1- and β3-integrin-dependent adhesion in endothelial cells and is involved in developmental and pathological angiogenesis
... b Fig. 5 Role of Arf GTPases for Brag2-mediated b1-integrin inter- nalization, angiogenic sprouting and regulation of focal/fibrillar adhesions. a Pulse-chased endocytosis assay of the b1-integrin subunit ...
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Cooperativity between Integrin Activation and Mechanical Stress Leads to Integrin Clustering.
... of integrin affinity towards their extracellular ligands by cytoplasmic proteins (inside-out signaling) these receptors bind to their ligands and cluster into nascent ...allosteric integrin activation works ...
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Chemomechanical regulation of integrin activation and cellular processes in acidic extracellular pH
... regarding integrin-ligand binding are addressed using molecular dynamics ...affect integrin activation? It is conceivable that protonation of specific amino acids on the integrin receptor in acidic ...
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Clustering and internalization of integrin alphavbeta3 with a tetrameric RGD-synthetic peptide.
... estimated that about 10% of v 3 /RAFT-RGD were forming integrin dimers. But, this percentage was most probably underestimated because we counted only the aggregates laying on the grid in a proper angle of ...
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