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Immuni response of the pig to respiratory diseases

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Immuni response of the pig

to

respiratory diseases

B. CHARLEY

Labnratoire de

Pathologie

Porcine, 1. X. R. :9., ., i8850

7’Àiv<iva/-<Jrignn>1

In the

respiratory

tract, the

major immunoglobulin

is

I g : I . Repeated lung washings

on

living pigs

demonstrated the presence of alveolar

macrophages

and

lymphocytcs.

During

an

experimental

swine influenza infection, BB’e observed a

systemic

ccll-mediated immune response, followed

by

an

independent

increase of local

(IgG

and

IgA)

and

systemic

anti-

bodies. Whereas serum antibodies

persisted,

local antibodies were

only

detectable

during

a

short

period.

Colostral

immunity

is able to reduce clinical

symptoms

of the disease, however inhibition of viral

replication

and release

requires

efficient local

immunity.

Classical swine fever. Duration of the immunity obtained

in

sows

by vaccination with the Thiverval strain

M. LAUNAIS,

J.-M. AYNAUD

1_abovatoire

Cogla,

Jnstitut

Biologique

de Libourne,

73. P.

126,

, 335(IO J i bo i<1>1<.

Laboratoire de

Pathologie

Porcine, 1. N. 12. ¿}., ., 78850

T h iverval- Grignon

Study

of the kinetics of serum antibodies

neutralizing

the swine fever virus enabled us to determine the characteristics of the

immunity

obtained after

one only injection

of a live vaccine

( T

hiverval strain)

to

gilts.

The

rapidly

obtained

immunity

reached a

high

level

(index

<

!)

and remained for at least 39

months at that

level,

thus

providing

an efficient

protection

to the

gilts during

their whole

reproductivc life.

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