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Production of α2,6-sialylated IgG1 in CHO cells

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Academic year: 2021

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Figure 1. Complex biantennary N-linked glycan structures found in the Fc domain of IgGs
Figure 2. Lectin-blot analyses of TZM from culture supernatants. Various amounts of glycosyltransferases and harvest time were tested for  opti-mal galactosylation and sialylation of the Fc
Table 1. Fc glycan composition of the wild-type TZM and F243A mutant expressed alone or co-expressed with GT, ST6 or both
Table 2 Incidence of terminal GlcNAc, galactose and sialic acid residues in the composition of the antennae of the complex glycans (i.e., the glycans pre- pre-sented in Table 1, except for the high-mannose and truncated-core categories) (rows 1, 2 and 3, r
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