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Characterization of DNA-binding activity of Zα domains from poxviruses and the importance of the β-wing regions in converting B-DNA to Z-DNA

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Academic year: 2021

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Figure

Figure 1. Sequence alignment of viral Za domains and related Za domains. It is shown underneath the secondary structure diagram, as revealed in the co-crystal structures of hZa ADAR1 , mZa ZBP1 and yabZa E3L (14–16)
Table 1. Z-DNA-binding affinities of viral Zas
Figure 2. The conversion of poly (dG–dC) from the B to Z conformation by Za. (A) Conversion of B-DNA to Z-DNA by Za proteins measured by CD in the range of 230–320 nm
Figure 5. Effects of hydrogen bond forming mutations at P-1 and P-2 in the variable regions of orfZa E3L on B to Z-DNA conversion activity.
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