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Rescue of biosynthesis of nicotinamide adenine dinucleotide protects the heart in cardiomyopathy caused by lamin A/C gene mutation

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Academic year: 2021

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Figure

Figure 1. NAD + salvage pathway is altered in LMNA cardiomyopathy (A) Schematic representation of the NAD + salvage pathway
Figure 2. NR supplementation leads to cardiac improvement in Lmna H222P/H222P mice. (A) Schematic representation of the treatment protocol of WT and Lmna H222P/H222P mice with NR
Table 1. Echocardiographic parameters for WT and Lmna H222P/H222P mice fed with either NR or chow diet
Figure 3. NAM supplementation does not improve cardiac function in Lmna H222P/H222P mice (A) Schematic representation of the treatment protocol of Lmna H222P/H222P mice with NAM
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