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Akt down-regulates ERK1/2 nuclear localization and angiotensin II-induced cell proliferation through PEA-15.

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Academic year: 2021

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Figure 3. Active Akt increases PEA-15 half-life independently of its binding to ERK1/2
Figure 5. PEA-15 overexpression decreases Elk-1– dependent tran- tran-scription, abolishes cFos expression, and inhibits cell proliferation induced by AngII without affecting ERK1/2 phosphorylation
Figure 7. Akt overexpression through PEA-15 decreases Elk-1– dependent transcription and cFos expression without affecting ERK1/2 activation

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