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Is it possible to detect G×E interactions in GWAS when causal exposure is unobserved?

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Academic year: 2021

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Table 1. Description of all simulated covariates and real genotypes for 1,191 individuals with 595 cases and 596 controls
Table 2. Association analysis performed on chromosome 6 with the four approaches, when the causal exposurer treatment is considered observed
Table 4. Advantages and disadvantages of studied methods when the SNP to detect interacts with an unobserved environmental exposure

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