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Wine polyphenols: potential agents in neuroprotection

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Wine polyphenols: potential agents in neuroprotection

Authors

Abdelkader Basli, Stéphanie Soulet, Nassima Chaher, Jean-Michel Mérillon, Mohamed Chibane, Jean-Pierre Monti, Tristan Richard

Publication date 2012/7/5

Source

Oxidative medicine and cellular longevity

Volume 2012

Publisher Hindawi

Description

There are numerous studies indicating that a moderate consumption of red wine provides certain health benefits, such as the protection against neurodegenerative diseases. This protective effect is most likely due to the presence of phenolic compounds in wine. Wine polyphenolic compounds are well known for the antioxidant properties. Oxidative stress is involved in many forms of cellular and molecular deterioration. This damage can lead to cell death and various neurodegenerative disorders, such as Parkinson’s or Alzheimer’s diseases. Extensive investigations have been undertaken to determine the neuroprotective effects of wine-related polyphenols. In this review we present the neuroprotective abilities of the major classes of wine-related polyphenols.

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