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Bicyclic eremophilane-type petasite sesquiterpenes potentiate peroxisome proliferator–activated receptor γ activator–mediated inhibition of dendritic cells

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Academic year: 2021

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Figure 1. PPARγ activation inhibits DC maturation and cytokine secretion. CD86 surface expression in BmDC after 3 h  preincubation with PPARγ agonists TGZ (5 and 10 µM), GW1929 (40 µM), and 15d-PGJ 2  (0.5 and 5 µM) followed by LPS overnight  stimulation w
Figure 2.  Bicyclic eremophilane-type petasite sesquiterpene ZYFDC21 potentiates the effects of PPARγ agonists on BmDC  maturation and activation
Figure 3.  Bicyclic eremophilane-type petasite sesquiterpene ZYFDC22 potentiate the effects of PPARγ agonists on BmDC  maturation and activation
Figure 4.  Petasite sesquiterpene ZYFDC21 in combination with GW1929 inhibited CD86 and cytokine secretion on BmDC
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