Modulation of voltage-gated potassium channels by phosphatidylinositol-4,5-bisphosphate

La meilleure compréhension de l’implication de ces canaux dans la phy- siologie de la nociception, ainsi que le développement d’une pharmacologie spécifique

Cells with higher acoustic contrast factor reach the nodal plane faster and can be collected in the central outlet while cells with a lower acoustic contrast factor stay on

Embayed beach; shoreline model; local geology; rotation; cross-shore migration; wave 28.. transformation

Les portes dites non-Clifford, quant à elles, permettent non seulement de se déplacer dans la sphère sur des états superposés avec un déphasage minime, mais aussi d’agir sur un

This orientation would thus mimic the P1-leucine side chain of the covalent bortezomib inhibitor co-crystallized with the human proteasome molecule or of the C-terminal benzylic

We used 3794 variants in the Genome Aggregation Database (gnomAD) (Karczewski et al., 2019) as variants with inferred neutral effects (see Table S2) during training of

In addition we also reported drug-induced use-dependent modifications of current peak and current tail, that have previously been proposed to result from (i) accumulation

Here we present a study in which electrophysiology and a Markovian multi-state modelling of the voltage-gated sodium channel were used to measure the susceptibility of the