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Epithelial stratification shapes infection dynamics

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Academic year: 2021

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Fig 1. Dynamics in the stratified epithelium. A) Basal and parabasal cells can divide either asymmetrically (1 − p 1 − p 2 and 1 − q 1 − q 2 respectively) or symmetrically, which result in two daughter cells of either the same (p 1 or q 1 ) or different ph
Table 1. Parameter descriptions for epithelial model, default values, biologically realistic ranges and estimated values
Fig 2. Epithelial cell growth in 3D raft cultures. A) NIKS grown from a single layer over a period of three weeks
Table 2. Sensitivity analyses of key infection properties. For each pathogen, we show the three most important parameters with the associated partial rank correlation coefficient (PRCC) and its 95% confidence interval
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