Chimeric hepatitis B virus/hepatitis C virus envelope proteins elicit broadly neutralizing antibodies and constitute a potential bivalent prophylactic vaccine.

Two animals that were vaccinated with BEI-inactivated virus in combination with Alhydrogel as adjuvant (group G) showed virus-specific antibodies from 2 weeks after the first

The highest titer increases for both Efb and LukM specific IgG1 and IgG2 antibody levels in serum and milk were observed following SC/SC immunizations.. Furthermore, the harmful

Keywords: hepatitis C virus; glycoprotein; envelope proteins; viral entry; viral assembly

patterns, there is a strong correlation between HCVpp and HCVcc in their sensitivity to antibody neutralization, indicating that the type of glycans associated with HCV

reported that an inactivated virus vaccine also protected mice and rhesus monkeys from ZIKV challenge by inducing E protein-specific neutralizing antibodies (Abbink et al., 2016;

Methods: Using H5N1 microneutralisation (MN) and H5-pseudotype particle-based microneutralisation assays (H5pp) we analyzed sera sequentially obtained from 11 severely ill

In this study, we developed an innovative approach in preventing HCV infection using a synergistic combination of a broadly neutralizing human monoclonal antibody (HMAb) targeting

Furthermore, viral evasion from host neutralizing antibodies has been revealed to be an important contributor in leading both to viral persistence in acute liver graft