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Apparent Diffusion Coefficient Histograms of Human Papillomavirus–Positive and Human Papillomavirus–Negative Head and Neck Squamous Cell Carcinoma: Assessment of Tumor Heterogeneity and Comparison with Histopathology

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Apparent Diffusion Coefficient Histograms of Human

Papillomavirus–Positive and Human Papillomavirus–Negative Head and Neck Squamous Cell Carcinoma: Assessment of Tumor

Heterogeneity and Comparison with Histopathology

DE PERROT, Thomas Benoît, et al.

Abstract

BACKGROUND AND PURPOSE: Head and neck squamous cell carcinoma associated with human papillomavirus infection represents a distinct tumor entity. We hypothesized that diffusion phenotypes based on the histogram analysis of ADC values reflect distinct degrees of tumor heterogeneity in human papillomavirus–positive and human papillomavirus–negative head and neck squamous cell carcinomas

DE PERROT, Thomas Benoît, et al . Apparent Diffusion Coefficient Histograms of Human Papillomavirus–Positive and Human Papillomavirus–Negative Head and Neck Squamous Cell Carcinoma: Assessment of Tumor Heterogeneity and Comparison with Histopathology.

American Journal of Neuroradiology , 2017, vol. 38, no. 11, p. 2153-2160

DOI : 10.3174/ajnr.A5370

Available at:

http://archive-ouverte.unige.ch/unige:99641

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