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Intravenous immunoglobulin mediates anti-inflammatory effects in peripheral blood mononuclear cells by inducing autophagy

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Academic year: 2021

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Fig. 1 IVIG induces autophagy in peripheral blood mononuclear cells. a PBMCs from healthy donors were cultured with IVIG (10 or 25 mg/ml) or HSA for 24 h
Fig. 2 IVIG induces autophagy in monocytes, dendritic cells and M1 macrophages but not in M2 macrophages
Fig. 3 Transmission electron microscopic analysis of autophagic organelles induced by IVIG in dendritic cells
Fig. 4 IVIG-induced autophagy in monocytes is associated with induction of class III PI3K, beclin-1, p-AMPK and p-p38MAPK and inhibition of p-mTOR
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