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The Clever Use of Pressure in Column Liquid Chromatography

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Academic year: 2021

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Fig. 1. Trivial and clever possibilities to work at higher pressure, here shown for the case of a fourfold pressure increase, with experimental van Deemter curves of two columns used in this paper
Table 1. Data of the columns used in this study expected to give the same separation performance
Figure 2 compares the separations of the doping agents with the three columns.
Fig. 3. Chromatograms obtained for the mixture of six pharmaceutical compounds with various Xbridge C18 columns, using an isocratic mobile phase consisting of 50% acetonitrile/50%

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