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Temocillin and piperacillin/tazobactam resistance by disc diffusion as antimicrobial surrogate markers for the detection of carbapenemase-producing Enterobacteriaceae in geographical areas with a high prevalence of OXA-48 producers

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Academic year: 2021

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Supplementary data

Table S1. Scattergram for a 10 μg meropenem (MEM) disc for 76 Enterobacteriaceae isolates by CLSI methodology

MEM MIC (mg/L)

MEM zone diameter (mm)

6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 ”0.25 1 1 3 1 3 2 1 2 0.5 1 2 1 1 2 3 4 1 1 3 2 2 1 1 2 1 1 2 1 1 2 4 1 8 2 3 1 1 1 1 16 1 1 32 1 1 1 >32 4 1 1 2 1 1 1 2 1 1

Table S2. Scattergram for a 100/10 μg piperacillin/tazobactam (TZP) disc for 76 Enterobacteriaceae isolates by CLSI methodology

TZP MIC (mg/L) TZP zone diameter (mm) 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 24 8 1 16 1 1 1 32 1 1 1 1 64 1 1 128 1 1 1 3 1 1 1 1 >128 17 6 6 9 5 8 2 2 1 Published in -RXUQDORI$QWLPLFURELDO&KHPRWKHUDS\  ± which should be cited to refer to this work.

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Table S3. Scattergram for a 30 μg temocillin (TMO) disc for 76 Enterobacteriaceae isolates by CLSI disc diffusion methodology and by Etest method

TMO MIC (mg/L)

TMO zone diameter (mm)

6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 6 1 8 1 1 1 12 2 1 1 16 1 1 24 1 2 1 32 1 1 4 3 48 1 1 1 1 1 1 64 2 3 1 1 96 1 2 128 3 1 192 1 2 1 256 4 384 2 1 512 1 1024 1 >1024 15 3 1 1

Figure

Table S1. Scattergram for a 10 μg meropenem (MEM) disc for 76 Enterobacteriaceae isolates by CLSI methodology
Table S3. Scattergram for a 30 μg temocillin (TMO) disc for 76 Enterobacteriaceae isolates by CLSI disc diffusion methodology and by Etest method

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