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Evidence for sequential and increasing activation of replication origins along replication timing gradients in the human genome.

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Academic year: 2021

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Table 1. Cells, DNA combing and replication timing datasets used in this study.
Figure 2. The global rate of DNA replication increases during S phase in HeLa cells. (A) Histogram of replication timing values (TR 50 , hours) in the whole genome
Figure 4. Characteristics of CTRs and TTRs. Blue, green and red curves respectively depict parameters defined at scales 100, 200 and 500 kb
Figure 8. DNA combing analysis of the IGH TTR. (A) Replication timing profile of the IGH region and its surroundings in HeLa cells
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