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An MVA vector expressing HIV-1 envelope under the control of a potent vaccinia virus promoter as a promising strategy in HIV/AIDS vaccine design

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Academic year: 2021

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Figure  1.  Generation  and  in  vitro  characterization  of  modified  vaccinia  virus  Ankara  (MVA)-  late/early  optimized  (LEO)160-gp120
Figure  2. MVA-LEO160-gp120  enhances  the  mRNA  levels  of  HIV-1  gp120,  compared  to  MVA-B
Figure 3. MVA-LEO160-gp120 enhances the protein levels of HIV-1 gp120, compared to MVA-B
Figure 4.  Immunization  with  DNA-gp120/MVA-LEO160-gp120  enhances  the  magnitude  of  HIV-1  Env-specific  CD4 +   and  CD8 +   T  cell  adaptive  immune  responses
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