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Cystathionine-γ-lyase expression is associated with mitochondrial respiration during sepsis-induced acute kidney injury in swine with atherosclerosis

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Academic year: 2021

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Table S2). Inflammatory cytokines TNF α and IL6, determined from the renal venous blood, were elevated in sepsis (Additional file 1: Table S2)
Fig. 2 Parameters of kidney function. a Physiological parameters: urine output, plasma creatinine (Creatinine), creatinine clearance (CrCl), and renal venous neutrophil gelatinase-associated lipocalin (NGAL) (all values sham n = 5, sepsis n = 8)
Fig. 3 Kidney specimens stained for nitrotyrosine formation (sham n = 5, sepsis n = 8) (a), albumin extravasation (sham n = 5, sepsis n = 8) (b), CSE expression (sham n = 5, sepsis n = 7) (c), and PGC1 α expression (sham n = 5, sepsis n = 8) (d)
Fig. 4 Mathematical correlations of PGC1 α expression, kidney function (CrCl), albumin extravasation, nitrotyrosine formation, mitochondrial activity to CSE expression, and mitochondrial activity to nitrotyrosine formation

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