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The selective peroxisome proliferator-activated receptor alpha modulator (SPPARMα) paradigm: conceptual framework and therapeutic potential

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Academic year: 2021

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Figure

Table 1 Prevalence of  elevated triglycerides and  atherogenic dyslipidemia in  the  general population and  high-risk  patient groups
Fig. 1  Remnant lipoproteins accumulate in the arterial wall where they elicit inflammation
Fig. 2  Genetic studies suggest novel approaches for the management of hypertriglyceridemia focused on key targets involved in the regulation of  triglyceride‑rich lipoprotein metabolism: apolipoprotein C‑III (encoded by APOC3), angiopoietin‑like proteins
Fig. 5  Structures of a SPPARMα (pemafibrate) and PPARα (fenofibrate) showing shared and unique regions
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