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Control of IFN-I responses by the aminopeptidase IRAP in neonatal C57BL/6 alveolar macrophages during RSV infection

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Academic year: 2021

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Figure

Fig. 1 Neonatal C57BL/6 mice are permissive to RSV infection and are unable to active an ef fi cient type I IFN pathway
Fig. 2 Adult or neonatal AMs collected from BAL of neonatal C57BL6 mice are activated upon RSV infection
Fig. 3 Intracellular localization of IRAP in adult or neonatal AMs. AMs collected from BAL of adult C57BL/6 mice or 6 days old C57BL/6 mice or 6 days old IRAP-de fi cient mice were plated for 24 h
Fig. 4 Deletion of IRAP restores type I IFN pathway in neonatal AMs following in vitro RSV infection
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