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Resistome analysis of a carbapenemase (OXA-48)-producing and colistin-resistant Klebsiella pneumoniae strain

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Partager "Resistome analysis of a carbapenemase (OXA-48)-producing and colistin-resistant Klebsiella pneumoniae strain"

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Published in "Antimicrobial Agents and Chemotherapy doi: 10.1128/AAC.00076-18, 2018"

which should be cited to refer to this work.

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blaOXA-48 100 AY236073 Carbapenems 2231 0.51 0.57

blaCTX-M-15 100 DQ302097 Extended-spectrum

Cephalosporins

10416 0.61 0.63

oqxA3 99.23 EU370913 Quinolones 194368 0.78 1.02

oqxB3 98.86 EU370913 Quinolones 194368 1.02 1.02

fosA3 97.62 NZ_AFBO01000747 Fosfomycin 362468 0.73 1.09

catA1 99.85 V00622 Phenicols 1204 0.95 0.83

tet(A) 100 AJ517790 Tetracycline 13075 0.64 0.61

dfrA30 99.58 AM997279 Trimethoprim 10416 0.71 0.63

Point mutations

Amino acid change

GyrA3 S83F, D87A - Quinolones 579439 1.12 0.99

ParC3 S80I - Quinolones 103616 1.14 1.07

MgrB3 N42Y, K43I - Colistin 227842 1.04 0.98

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