• Aucun résultat trouvé

Aag-initiated base excision repair promotes ischemia reperfusion injury in liver, brain, and kidney

N/A
N/A
Protected

Academic year: 2021

Partager "Aag-initiated base excision repair promotes ischemia reperfusion injury in liver, brain, and kidney"

Copied!
10
0
0

Texte intégral

Loading

Figure

Fig. 1. Aag deficiency protects liver against I/R-induced tissue damage. (A) The BER pathway initiated by various DNA glycosylases consists of four key enzymatic steps: (i) glycosylase-mediated excision of a damaged base generating an abasic site; (ii) inc
Fig. 2. WT mice accumulate more BER intermediates and fewer 8-oxoG DNA lesions than Aag −/− mice
Fig. 3. Parylation is differentially induced by I/R in WT vs. Aag −/− liver. (A) Images of livers from WT sham-operated mice and mice that have undergone I/R (90 min, 24 h) are shown
Fig. 4. Differential Hmgb1 translocation phenotypes between WT and Aag −/− mice upon I/R
+3

Références

Documents relatifs

Afin de déterminer si une source de tension auxiliaire est nécessaire pour réaliser la source telle que décrite dans [5], le réseau domestique a été mesuré. Tout d’abord, la

Pour mieux cerner la promotion de cette participation des usagers dans la gouvernance des centres de santé au niveau périphérique et se fondant sur des

From here, several injury cascades are activated, including activation of cell death programs like apoptosis and (regulated) necrosis, endothelial dysfunction implicating

We have demonstrated, both in vitro and in vivo models of ischemic stress as it occurs during cold ischemia, that kidney epithelial cells subjected to glucose deprivation

A comparison of hypothermic machine perfusion versus static cold storage in an experimental model of renal ischemia reperfusion injury. Renoprotective effect of pulsatile

If the player B had a winning strategy in the original game starting from a given position then he keeps playing according to its original strategy as long as the player A keeps

We choose a very mild near-zero slope (γ =0.001), but not exactly zero since otherwise no meaningful comparison would be possible be- tween the traditional and non-traditional

Dans le même registre, on peut lire, vers la fin de Projet pour une révolution à New York, tout un passage où le narrateur exprime ce dont il aurait encore dû parler mais qu’il