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A new diagnostic algorithm for Burkitt and diffuse large B-cell lymphomas based on the expression of CSE1L and STAT3 and on MYC rearrangement predicts outcome

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Academic year: 2021

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Table 1. Immunohistochemical and genetic characteristics of all cases All cases n (%) BLn (%) DLBCLn(%) Intermediate DLBCL/BLn(%) P value Total 242 (100.0) 22 (9.1) 193 (79.8) 27 (11.2) Age at diagnosis <0.001 Median 60.5 37.5 63 54 Mean 58.1 38.6 61.2
Table 2. Clinical characteristics of the patients
Figure 1. Results of immunohistochemical markers. ’CSE1L’ in reactive lymphoid tissue at (A) low (20×) and (B) high power (40×) magnification with predominant, cytoplasmic reactivity in germinal-center dark cells and less strong in the light zone, but not i
Figure 2. Decision trees trained to predict the diagnosis of either Burkitt’s lymphoma (BL) or diffuse large B-cell lymphoma (DLBCL) with different sets of markers and FISH results (n = 248)
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