The diverse members of the mammalian HSP70 machine show distinct chaperone-like activities
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(15) Biochemical Journal Immediate Publication. Published on 14 Jan 2011 as manuscript BJ20101247. . us cri pt. ) 9 -% B % B% ;% $ % ;% >2001@ # #6# 6 % :;< +/. JJ 2 H% # % 5% % ;% >200J@ +0 & # < %%5 % %= )*. an. 8 % H% % !% >)**1@ = 6 )2 %;% %:>? )22*.)2,+ /% %<M9 %=%H9 '%H;%>200/@'J 6 %' % % %:< )1/*.)11*. dM. 1 % 5% % ;% >)**J@ ;& % %%> 2J.,1 + % % ; % >200+@ = 6 +0 & ' # % 5H %?=: ,+02.,+)0. pte. J9%%>200)@= 9 6# % $ %=%%%H % %>?9 ),,.)8/ * %%%$% % %!%>)**/@! '+0 =$ 9 9 # ';.)%5A;%:< 22J).22*2. ce. )0 ;% 5% A 6 (% ' % % >)**8@ 9 # % > ))).))+ )) 4$%"#<# %M <% %( "%H%>200)@F ( . 5 F . C F .( %;% %%;9 +*01.+*)2. Ac. THIS IS NOT THE VERSION OF RECORD - see doi:10.1042/BJ20101247. , % H% ( % B% % % $ 6 -% B% " 6 '% % (% (%%(96 %5%( '%'%>200+@ . '2+ >')@ % %;%< 80+.8)+. )2 9 %H -% % 5%% %$% >)***@ +0 >(@ C '$+0 6 % ;% %:=: 8,8.88,. . Licenced copy. Copying is not permitted, except with prior permission and as allowed by law. © 2011 The Authors Journal compilation © 2011 Portland Press Limited. .
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(17) Biochemical Journal Immediate Publication. Published on 14 Jan 2011 as manuscript BJ20101247. 21 % %(%( %"%A 6(% A%( '%'% >)**+@'+0'80 %;% %%;; ,,2J,.,,2J*. us cri pt. 2+ % % -%=% ( %"% ( '% '% A% >)**/@ = 9 . 4 % 9 < %5 %;% %;>< ,J2.,J* 2J B% ' ;% A 6 (% ' % % >)**1@ .6 +0 9 ; '80%;% %% ;: )*1)+. )*128. an. ,0 5% % ;% %;%( '%'% % !% >2000@ ) '+0 % % % ; )0J,. )0JJ ,) 5% % ' # H% >200J@ '+0T '+2 4 9 %54% %. dM. ,2 5%;% % ' #H% 5% >200J@ 4 '+0T 9 % %%:> )0/.))0 ,,5%;%$ % % %' #H%5%>200+@'+0T % %%:; 2)*.22*. pte. ,85%;%$ % % %;% %' #H%5%>200+@ 9. '+0T 4 & 4 % ;% $ ;: 20).2)) ,/ $ % % >)**1@ =- #& % % % %:; ,/+.,/J ,1 F % % ( '% '% % % >200+@ 9 '+0 %54% %>:> ,/1J.,/+J. . ce. ,+ % 5% %>200+@ #6 ; %$% % % %%% :< +)1,.+)1J ,J9 % %$ 5% 6#6%M < % #6 "%( < 6 ;% % $ % H % ' ;% = 5% H% = % % >200J@ = 'A. # '*0 )% 5H %?=; )+JJ.)+*8. Ac. THIS IS NOT THE VERSION OF RECORD - see doi:10.1042/BJ20101247. 2* 5% % ;% % '%"9H% % ( '%'%>)***@! 6 +0 % % %:@ 201*. 20+*. ,* '% H=% ' % % 6 % >)**,@ ( ; 5 9 . %5A;%:; 8),+.8)88. . Licenced copy. Copying is not permitted, except with prior permission and as allowed by law. © 2011 The Authors Journal compilation © 2011 Portland Press Limited. .
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(19) Biochemical Journal Immediate Publication. Published on 14 Jan 2011 as manuscript BJ20101247. 4/4 . ce. pte. dM. an. us cri pt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c. THIS IS NOT THE VERSION OF RECORD - see doi:10.1042/BJ20101247. . . Licenced copy. Copying is not permitted, except with prior permission and as allowed by law. © 2011 The Authors Journal compilation © 2011 Portland Press Limited. .
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(22) Biochemical Journal Immediate Publication. Published on 14 Jan 2011 as manuscript BJ20101247. Figure 1 A unicellular eukaryotes. compartmentalization multi-domain proteins. 15. 80. 5. 60 40 20. S. cerevisiae C. elegans D. melanogaster H. sapiens A. thaliana. Eubacteria. Eukaryota. Archaea. Eubacteria. Eukaryota. an. S. aureus M. pneumoniae E. coli Y. pestis angola. Archaea. Ac. ce. pte. dM. T. kodakaraensis M. jannaschii T. acidophilum M. mazei. 0. S. cerevisiae C. elegans D. melanogaster H. sapiens A. thaliana. 10. DNAJ. S. aureus M. pneumoniae E. coli Y. pestis angola. Number of genes. 100. us cri pt. C. 20. 0. THIS IS NOT THE VERSION OF RECORD - see doi:10.1042/BJ20101247. multi cellularity cellular specialization development. DNAK/HSPA. Number of genes. B. multicellular eukaryotes. T. kodakaraensis M. jannaschii T. acidophilum M. mazei. prokaryotes. Licenced copy. Copying is not permitted, except with prior permission and as allowed by law. © 2011 The Authors Journal compilation © 2011 Portland Press Limited.
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