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Both base excision repair and O-6-methylguanine-DNA methyltransferase protect against methylation-induced colon carcinogenesis

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Academic year: 2021

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Figure

Fig. 1. Experimental protocol and mortality of WT, Mgmt / , Aag / and Mgmt / /Aag / mice in the AOM/DSS model
Fig. 2. Increased acute mucosal inflammation in Mgmt / and Mgmt / / Aag / versus Aag / and WT mice after administration of AOM/DSS
Fig. 5. Tumor histology and intestinal epithelial cell apoptosis following AOM administration

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