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Prognostic value of peripheral blood double detection of CK19 and MUC1 mRNA positive cells detected by RT-quantitative PCR in 94 breast cancer patients with a follow up of 9 years.

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HAL Id: inserm-00288138

https://www.hal.inserm.fr/inserm-00288138

Submitted on 15 Jun 2008

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Prognostic value of peripheral blood double detection of

CK19 and MUC1 mRNA positive cells detected by

RT-quantitative PCR in 94 breast cancer patients with a

follow up of 9 years.

Jean-Yves Pierga, François-Clément Bidard, Marc Denis, Patricia de Cremoux

To cite this version:

Jean-Yves Pierga, François-Clément Bidard, Marc Denis, Patricia de Cremoux. Prognostic value of pe-ripheral blood double detection of CK19 and MUC1 mRNA positive cells detected by RT-quantitative PCR in 94 breast cancer patients with a follow up of 9 years.. Molecular Oncology, Elsevier, 2007, 1 (3), pp.267-8. �10.1016/j.molonc.2007.09.005�. �inserm-00288138�

(2)

Figure 1:

Overall survival in high risk breast cancer patients (stage III and IV, n=48) according to CTC status (MUC1 and/or CK19 positive)

0 ,2 ,4 ,6 ,8 1

%

S

u

rv

iv

a

l

0

24

48

72

96

120

Months

CTC negative

CTC positive

p=0.0021

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